Renal Perfusion and the Development of AKI Following Traumatic Injury - A Longitudinal Observational Cohort Study
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY
Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known to develop hypoperfusion of the renal cortex, little is known regarding intra-renal perfusion changes in THS. The aim of the current study is to investigate the effects of THS on renal microcirculatory perfusion.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age \> 18 years
• Within 24 hours of ICU admission following traumatic injury
• Received any blood products during initial resuscitation
• Lactate \> 2 mmol/l at any stage prior to study enrolment
Locations
Other Locations
United Kingdom
King's College Hospital
RECRUITING
London
Contact Information
Primary
Sam Hutchings
sam.hutchings@nhs.net
+442032994957
Time Frame
Start Date: 2024-04-13
Estimated Completion Date: 2026-07
Participants
Target number of participants: 20
Treatments
Traumatic haemorrhagic shock
Related Therapeutic Areas
Sponsors
Leads: King's College Hospital NHS Trust