Impact of Prophylactic Antibiotics on Bloodstream Infections After Liberation From Extracorporeal Membrane Oxygenation
Status: Not yet recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this prospective interventional study is to evaluate the impact of antibiotic prophylaxis on bloodstream infections after liberation of extracorporeal membrane oxygenation therapy. The main questions aims to answer are: • does application of vancomycine prior to ECMO liberation have an impact of bloodstream infections? Participants will get 1 dose of vancomycine I.V. (15-20 mg per kgKG) prior to liberation of ECMO. Researchers will compare this interventional group to a group without antibiotic prophylaxis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: No
View:
• adult patients older than 18 years
• ECMO-Therapy
Locations
Other Locations
Germany
University Hospital of Saarland
Homburg
Contact Information
Primary
Carsten Zeiner, MD
carsten.zeiner@uks.eu
+49684116
Backup
Philipp M Lepper, MD
philipp.lepper@uks.eu
+49684116
Time Frame
Start Date: January 1, 2023
Estimated Completion Date: December 31, 2023
Participants
Target number of participants: 42
Treatments
Active Comparator: Intervention: Prophylactic antibiotic treatment
Application of 15-20 mg per kgKG Vancomycine I.V. prior to ECMO liberation
No Intervention: Control Arm: No prophylactic antibiotic treatment
Control group - no intervention.
Authors
Related Therapeutic Areas
Sponsors
Leads: Universität des Saarlandes