Point of Care Evaluation of Fibrinolysis in Sepsis
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Impaired fibrinolysis in septic patients is associated with worse outcome. The present study investigates fibrinolysis shutdown in septic patients, defined as prolonged ClotPro® TPA lysis time at 30 minutes. The TPA lysis time reference range is established in a cohort of healthy volunteers.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• age \> 18 years
• sepsis or septic shock
• vasopressors required to maintain a MAP ≥ 65 mmHg despite adequate fluid resuscitation
Locations
Other Locations
Italy
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
RECRUITING
Milan
Time Frame
Start Date: 2024-01-22
Estimated Completion Date: 2025-08-31
Participants
Target number of participants: 100
Treatments
Other: Septic patients
Other: Healthy volunteers
Related Therapeutic Areas
Sponsors
Leads: Policlinico Hospital