Assessment of Intra-thoracic Water by Bio Reactance During Stabilization and Therapeutic De-escalation in Septic Shock: A Prospective, Multicenter, Observational Study

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

In ICU, fluid challenge represents one of the cornerstones of hemodynamic care. However, fluid overload due to an excessive and/or inappropriate fluid administration could be associated with morbidity or mortality. Unfortunately, there is currently no continuous non-invasive devices to monitor fluid content at bedside. Bio reactance is a non-invasive, rapid and continuous technology developed in order to measure body fluid compartment. Monitoring devices functioning with such technology are promising to evaluate fluid overload in ICU.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:

• Adult (Age \>18 years old)

• Septic shock according to Sepsis-3 definition:

‣ A suspected or confirmed infection

⁃ Persisting hypotension, despite adequate fluid resuscitation, requiring vasopressor to maintain a Mean Arterial Pressure (MAP) ≥ 65 mmHg

⁃ Lactate level \> 2 mmol/l

• Predictive ICU length of stay \> 3 days

Locations
Other Locations
France
Chu Brest
RECRUITING
Brest
Hegp - Aphp
NOT_YET_RECRUITING
Paris
Contact Information
Primary
Xavier Chapalain, MD
xavier.chapalain@chu-brest.fr
+33230337893
Backup
Dauphou Eddi
dauphou.eddi@chu-brest.fr
Time Frame
Start Date: 2023-06-01
Estimated Completion Date: 2025-06-01
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Brest

This content was sourced from clinicaltrials.gov