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Triage Performance and Physiological Parameters Predicting Serious Illness in Children Presenting With Fever to the Pediatric Emergency Department: A Multicenter Prospective Cohort Study

Status: Recruiting
Location: See all (10) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This multicenter prospective observational cohort study evaluates how well the initial triage category assigned by the Turkish Ministry of Health three-level color-coded triage system (Red-Yellow-Green) predicts serious clinical outcomes in children aged 0-18 years who present with fever to pediatric emergency departments. The study additionally assesses whether physiological parameters recorded at triage (heart rate, respiratory rate, oxygen saturation, capillary refill time, AVPU level of consciousness, and general appearance) provide independent and incremental prognostic value beyond the assigned triage category. Ten centers across Turkey will enroll consecutive eligible febrile children over a 3-month period. Routine clinical care and triage decisions are not altered by the study. The primary outcome is a composite serious clinical outcome. The study is reported in accordance with the STROBE and TRIPOD statements.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 18
Healthy Volunteers: f
View:

• Age 0-18 years

• Presentation to the pediatric emergency department

• Fever \>=38.0 C at triage OR history of fever within the preceding 24 hours

Locations
Other Locations
Turkey
Adana City Training and Research Hospital
RECRUITING
Adana
Cukurova University Faculty of Medicine
RECRUITING
Adana
Akdeniz University Faculty of Medicine
RECRUITING
Antalya
Osmangazi University Faculty of Medicine
RECRUITING
Eskişehir
Kartal Dr. Lutfi Kirdar City Hospital
RECRUITING
Istanbul
Dokuz Eylul University Faculty of Medicine
RECRUITING
Izmir
Erciyes University Faculty of Medicine
RECRUITING
Kayseri
Kayseri City Hospital
RECRUITING
Kayseri
Celal Bayar University Faculty of Medicine
RECRUITING
Manisa
Tokat University Faculty of Medicine
RECRUITING
Tokat Province
Contact Information
Primary
Yilmaz Secilmis, MD
yilmazsecilmis@erciyes.edu.tr
+905063013174
Time Frame
Start Date: 2026-07-28
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 3000
Treatments
Febrile children in the pediatric emergency department
Children aged 0-18 years presenting with fever (\>=38.0 C at triage or history of fever within the preceding 24 hours) to a participating pediatric emergency department during the 3-month study period. All undergo routine triage with the Ministry of Health three-level color-coded system; triage decisions and clinical care are not altered by the study.
Related Therapeutic Areas
Sponsors
Collaborators: Dokuz Eylul University, Tokat Gaziosmanpasa University, Akdeniz University, Eskisehir Osmangazi University, Manisa Celal Bayar University, Lütfi Kırdar City Hospital, Kayseri City Hospital, Adana City Training and Research Hospital, Cukurova University
Leads: TC Erciyes University

This content was sourced from clinicaltrials.gov