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Learn About Sertoli Cell-Only Syndrome

What is the definition of Sertoli Cell-Only Syndrome?
Sertoli cell-only syndrome (SCO syndrome) is a cause of male infertility. In SCO syndrome, only Sertoli cells (cells that nurture the immature sperm) line the seminiferous tubules (tubes inside the testicles where sperm develop). Therefore, there are not any sperm cells present in the seminiferous tubules. Men typically learn they are affected when being evaluated for infertility and are found to have no sperm production (azoospermia). Other signs and symptoms are rare, but in some cases there could be an underlying cause of SCO syndrome that causes other symptoms, such as Klinefelter syndrome. Most cases of SCO syndrome are idiopathic (of unknown cause), but causes may include deletions of genetic information on regions of the Y-chromosome, especially on the azoospermia factor (AZF) region of Y-chromosome. Other causes include exposure to chemicals or toxins, history of radiation therapy, and history of severe trauma. Diagnosis of SCO syndrome is confirmed with testicular biopsy.
What are the alternative names for Sertoli Cell-Only Syndrome?
  • Sertoli cell-only syndrome
  • Del Castillo syndrome
  • Germinal cell aplasia
Who are the top Sertoli Cell-Only Syndrome Local Doctors?
Elite in Sertoli Cell-Only Syndrome
Elite in Sertoli Cell-Only Syndrome
525 E 68th St # F-905a, 
New York, NY 
Languages Spoken:
English

Peter Schlegel is an Urologist in New York, New York. Dr. Schlegel is rated as an Elite provider by MediFind in the treatment of Sertoli Cell-Only Syndrome. His top areas of expertise are Klinefelter Syndrome, Sertoli Cell-Only Syndrome, Infertility, Vasectomy, and Hormone Replacement Therapy (HRT).

Elite in Sertoli Cell-Only Syndrome
Elite in Sertoli Cell-Only Syndrome
Asahikawa, JP 

Toshinobu Miyamoto practices in Asahikawa, Japan. Miyamoto is rated as an Elite expert by MediFind in the treatment of Sertoli Cell-Only Syndrome. Their top areas of expertise are Sertoli Cell-Only Syndrome, Encephalocele, Small for Gestational Age, and Infertility.

 
 
 
 
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Paulette R. Shin
Advanced in Sertoli Cell-Only Syndrome
Advanced in Sertoli Cell-Only Syndrome

Shady Grove Fertility - K Street, D.C.

2021 K Street, Suite 101, 
Washington, DC 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Paul R. Shin, M.D., earned his undergraduate degree with distinction in biology and his medical degree from the University of Virginia School of Medicine, Charlottesville, VA. Before starting his residency he completed a 1 year internship in general surgery with the Emory University Hospitals and Clinics, Atlanta, GA. He continued on to complete his residency in urology at the University of Virginia before heading to the Cleveland Clinic Foundation’s Glickman Urological Institute to complete his fellowship in male infertility. Dr. Shin was an Executive Board Member for the Society for the Study of Male Reproduction (SSMR) from 2011 to 2013 and Program Chair for the 2012 SSMR meeting. He served on the Strategic Planning Committee for the American Society of Andrology meeting in 2014. Dr. Shin has served on the Urology Care Foundation’s Reproductive and Sexual Health Committee since 2014, and is currently a Society for Male Reproduction and Urology (SMRU) Board Member (Member-at-Large). He has been a member of the Continuing Medical Education Committee of the American Society for Reproductive Medicine since 2014. Dr. Shin is board certified in urology and joined the practice in 2015. Dr. Shin is rated as an Advanced provider by MediFind in the treatment of Sertoli Cell-Only Syndrome. His top areas of expertise are Sertoli Cell-Only Syndrome, Spermatogenesis Arrest, Varicocele, and Infertility.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center