Sertoli Cell-Only Syndrome Overview

Save information for later
Sign Up

Learn About Sertoli Cell-Only Syndrome

What is the definition of Sertoli Cell-Only Syndrome?
Sertoli cell-only syndrome (SCO syndrome) is a cause of male infertility. In SCO syndrome, only Sertoli cells (cells that nurture the immature sperm) line the seminiferous tubules (tubes inside the testicles where sperm develop). Therefore, there are not any sperm cells present in the seminiferous tubules. Men typically learn they are affected when being evaluated for infertility and are found to have no sperm production (azoospermia). Other signs and symptoms are rare, but in some cases there could be an underlying cause of SCO syndrome that causes other symptoms, such as Klinefelter syndrome. Most cases of SCO syndrome are idiopathic (of unknown cause), but causes may include deletions of genetic information on regions of the Y-chromosome, especially on the azoospermia factor (AZF) region of Y-chromosome. Other causes include exposure to chemicals or toxins, history of radiation therapy, and history of severe trauma. Diagnosis of SCO syndrome is confirmed with testicular biopsy.
What are the alternative names for Sertoli Cell-Only Syndrome?
  • Sertoli cell-only syndrome
  • Del Castillo syndrome
  • Germinal cell aplasia
Who are the top Sertoli Cell-Only Syndrome Local Doctors?
Dr. Martin N. Kathrins
Urology
Dr. Martin N. Kathrins
Urology

Brigham And Womens Physicians Organization Inc

45 Francis St, 
Boston, MA 
 (0.8 mi)
617-732-5500
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Martin Kathrins is an Urologist in Boston, Massachusetts. Dr. Kathrins and is rated as a Distinguished provider by MediFind in the treatment of Sertoli Cell-Only Syndrome. His top areas of expertise are Sertoli Cell-Only Syndrome, Varicocele, Infertility, Vasectomy, and Ureteroscopy. Dr. Kathrins is currently accepting new patients.

Dr. Robert D. Oates
Urology
Dr. Robert D. Oates
Urology

Boston University Medical Center Urologists, Inc.

725 Albany St, Suite 3b, 
Boston, MA 
 (2.5 mi)
617-638-8485
Experience:
43+ years
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Robert Oates is an Urologist in Boston, Massachusetts. Dr. Oates has been practicing medicine for over 43 years and is rated as a Distinguished provider by MediFind in the treatment of Sertoli Cell-Only Syndrome. His top areas of expertise are Sertoli Cell-Only Syndrome, Klinefelter Syndrome, Infertility, and Spermatogenesis Arrest. Dr. Oates is currently accepting new patients.

 
 
 
 
Learn about our expert tiers
Learn More
Mark D. Hornstein
Dr. Mark D. Hornstein
Reproductive Medicine | Obstetrics and Gynecology
Dr. Mark D. Hornstein
Reproductive Medicine | Obstetrics and Gynecology

Brigham And Womens Physicians Organization Inc

75 Francis St, 
Boston, MA 
 (0.8 mi)
617-732-5500
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Mark Hornstein is a Reproductive Medicine specialist and an Obstetrics and Gynecologist in Boston, Massachusetts. Dr. Hornstein and is rated as an Advanced provider by MediFind in the treatment of Sertoli Cell-Only Syndrome. His top areas of expertise are Endometriosis, Infertility, Sertoli Cell-Only Syndrome, and Neuralgia. Dr. Hornstein is currently accepting new patients.

View All Doctors
What are the latest Sertoli Cell-Only Syndrome Clinical Trials?
Match to trials
Find the right clinical trials for you in under a minute
Get started
View All Clinical Trials
Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center