Learn About Short QT Syndrome

What is the definition of Short QT Syndrome?

Short QT syndrome is a condition that can cause a disruption of the heart's normal rhythm (arrhythmia). In people with this condition, the heart (cardiac) muscle takes less time than usual to recharge between beats. The term "short QT" refers to a specific pattern of heart activity that is detected with an electrocardiogram (EKG), which is a test used to measure the electrical activity of the heart. In people with this condition, the part of the heartbeat known as the QT interval is abnormally short.

Save information for later
Sign Up
What are the causes of Short QT Syndrome?

Mutations in the KCNH2, KCNJ2, and KCNQ1 genes can cause short QT syndrome. These genes provide instructions for making channels that transport positively charged atoms (ions) of potassium out of cells. In cardiac muscle, these ion channels play critical roles in maintaining the heart's normal rhythm. Mutations in the KCNH2, KCNJ2, or KCNQ1 gene increase the activity of the channels, which enhances the flow of potassium ions across the membrane of cardiac muscle cells. This change in ion transport alters the electrical activity of the heart and can lead to the abnormal heart rhythms characteristic of short QT syndrome.

How prevalent is Short QT Syndrome?

Short QT syndrome appears to be rare. At least 70 cases have been identified worldwide since the condition was discovered in 2000. However, the condition may be underdiagnosed because some affected individuals never experience symptoms.

Is Short QT Syndrome an inherited disorder?

Short QT syndrome appears to have an autosomal dominant pattern of inheritance, which means one copy of the altered gene in each cell is sufficient to cause the disorder. Some affected individuals have a family history of short QT syndrome or related heart problems and sudden cardiac death. Other cases of short QT syndrome are classified as sporadic and occur in people with no apparent family history of related heart problems.

Who are the top Short QT Syndrome Local Doctors?
Elite
Highly rated in
35
conditions

Medical Faculty Mannheim

First Department Of Medicine 
Mannheim, BW, DE 

Ibrahim Akin practices in Mannheim, Germany. Akin is rated as an Elite expert by MediFind in the treatment of Short QT Syndrome. He is also highly rated in 35 other conditions, according to our data. His top areas of expertise are Cardiogenic Shock, Short QT Syndrome, Heart Attack, and Cardiomyopathy.

Elite
Highly rated in
8
conditions

University Of Bristol

University Walk 
Bristol, ENG, GB 

Jules Hancox practices in Bristol, United Kingdom. Hancox is rated as an Elite expert by MediFind in the treatment of Short QT Syndrome. He is also highly rated in 8 other conditions, according to our data. His top areas of expertise are Short QT Syndrome, Long QT Syndrome, Ventricular Tachycardia, and Arrhythmias.

 
 
 
 
Learn about our expert tiers
Learn more
Elite
Highly rated in
15
conditions

Klinikum Ludwigsburg

Mannheim, BW, DE 

Christian Wolpert practices in Mannheim, Germany. Wolpert is rated as an Elite expert by MediFind in the treatment of Short QT Syndrome. He is also highly rated in 15 other conditions, according to our data. His top areas of expertise are Short QT Syndrome, Fainting, Andersen-Tawil Syndrome, and Ventricular Fibrillation.

What are the latest Short QT Syndrome Clinical Trials?
China Inherited Ventricular Arrhythmias Registry, a Multicenter, Observational and Prospective Study
Match to trials
Find the right clinical trials for you in under a minute
Get started
Who are the sources who wrote this article ?

Published Date: June 01, 2013Published By: National Institutes of Health

What are the Latest Advances for Short QT Syndrome?
Long-term follow-up of implantable cardioverter-defibrillators in Short QT syndrome.
Quinidine-A legacy within the modern era of antiarrhythmic therapy.
Tired of the same old research?
Check Latest Advances
Overlap Arrhythmia Syndromes Resulting from Multiple Genetic Variations Studied in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.