Learn About Sick Sinus Syndrome

What is the definition of Sick Sinus Syndrome?

Sick sinus syndrome (also known as sinus node dysfunction) is a group of related heart conditions that can affect how the heart beats. "Sick sinus" refers to the sino-atrial (SA) node, which is an area of specialized cells in the heart that functions as a natural pacemaker. The SA node generates electrical impulses that start each heartbeat. These signals travel from the SA node to the rest of the heart, signaling the heart (cardiac) muscle to contract and pump blood. In people with sick sinus syndrome, the SA node does not function normally. In some cases, it does not produce the right signals to trigger a regular heartbeat. In others, abnormalities disrupt the electrical impulses and prevent them from reaching the rest of the heart.

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What are the causes of Sick Sinus Syndrome?

Sick sinus syndrome can result from genetic or environmental factors. In many cases, the cause of the condition is unknown.

How prevalent is Sick Sinus Syndrome?

Sick sinus syndrome accounts for 1 in 600 patients with heart disease who are over age 65. The incidence of this condition increases with age.

Is Sick Sinus Syndrome an inherited disorder?

Most cases of sick sinus syndrome are not inherited. They are described as sporadic, which means they occur in people with no history of the disorder in their family.

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What are the latest Sick Sinus Syndrome Clinical Trials?
ATrial Tachycardia PAcing Therapy in Congenital Heart

Summary: Congenital heart disease (CHD) affects approximately 1% of newborns in the US, with 25% of those affected having critical conditions requiring open heart surgery within one year of birth. Surgical and medical advances have allowed many patients to live beyond their fourth and fifth decades of life. Unfortunately, cardiac arrhythmias are a relatively common sequela due to cardiac anomalies and surg...

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Physiological Ventricular Pacing Versus Managed Ventricular Pacing for Persistent Atrial Fibrillation Prevention in Patients With Prolonged Atrioventricular Interval: a Multicenter RCT

Summary: A multicenter, prospective, randomized study in a 1:1 ratio, single-blind with double-blind evaluation to evaluate the superiority of physiological ventricular pacing (proposed modality) vs. managed ventricular pacing (control) for prevention of persistent AF (PeAF) occurrence in patients with prolonged atrioventricular interval (PR≥180 ms) and indication for pacing: sinus node disease and/or paro...

Who are the sources who wrote this article ?

Published Date: August 01, 2013Published By: National Institutes of Health

What are the Latest Advances for Sick Sinus Syndrome?
A 15-year follow-up study of radiofrequency catheter ablation for atrial fibrillation in patients with tachycardia-bradycardia syndrome.
Clinical case of the cardiovascular system involvement in a patient with Charcot-Marie-Tooth disease.
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Cyclosporine for the treatment of multisystem inflammatory syndrome in children with coronary artery aneurysms.