Sick Sinus Syndrome Overview
Learn About Sick Sinus Syndrome
Sick sinus syndrome (also known as sinus node dysfunction) is a group of related heart conditions that can affect how the heart beats. "Sick sinus" refers to the sino-atrial (SA) node, which is an area of specialized cells in the heart that functions as a natural pacemaker. The SA node generates electrical impulses that start each heartbeat. These signals travel from the SA node to the rest of the heart, signaling the heart (cardiac) muscle to contract and pump blood. In people with sick sinus syndrome, the SA node does not function normally. In some cases, it does not produce the right signals to trigger a regular heartbeat. In others, abnormalities disrupt the electrical impulses and prevent them from reaching the rest of the heart.
Sick sinus syndrome can result from genetic or environmental factors. In many cases, the cause of the condition is unknown.
Sick sinus syndrome accounts for 1 in 600 patients with heart disease who are over age 65. The incidence of this condition increases with age.
Most cases of sick sinus syndrome are not inherited. They are described as sporadic, which means they occur in people with no history of the disorder in their family.
Giuseppe Boriani practices in Modena, Italy. Boriani is rated as an Elite expert by MediFind in the treatment of Sick Sinus Syndrome. Their top areas of expertise are Atrial Fibrillation, Heart Failure, Stroke, Cardiac Ablation, and Transcatheter Aortic Valve Replacement (TAVR).
Atrium Health Sanger Heart & Vascular Institute Kenilworth
John Holshouser is a Cardiologist and a Cardiac Electrophysiologist in Charlotte, North Carolina. Dr. Holshouser is rated as a Distinguished provider by MediFind in the treatment of Sick Sinus Syndrome. His top areas of expertise are Arrhythmias, Sick Sinus Syndrome, Ventricular Tachycardia, Pacemaker Implantation, and Cardiac Ablation. Dr. Holshouser is currently accepting new patients.
Atrium Health Sanger Heart & Vascular Institute Kenilworth
John Fedor is a Cardiologist and a Cardiac Electrophysiologist in Charlotte, North Carolina. Dr. Fedor is rated as a Distinguished provider by MediFind in the treatment of Sick Sinus Syndrome. His top areas of expertise are Arrhythmias, Atrial Fibrillation, Sick Sinus Syndrome, Pacemaker Implantation, and Cardiac Ablation. Dr. Fedor is currently accepting new patients.
Summary: The purpose of the BIO-CONDUCT study is to demonstrate the safety and effectiveness of the BIOTRONIK Solia CSP S pacing lead when implanted in the left bundle branch area (LBBA). Safety will be assessed by evaluating serious adverse device effects that occur through 3 months post-implant. Efficacy will be assessed by evaluating implant success rate.
Summary: A multicenter, prospective, randomized study in a 1:1 ratio, single-blind with double-blind evaluation to evaluate the superiority of physiological ventricular pacing (proposed modality) vs. managed ventricular pacing (control) for prevention of persistent AF (PeAF) occurrence in patients with prolonged atrioventricular interval (PR≥180 ms) and indication for pacing: sinus node disease and/or paro...
Published Date: August 01, 2013
Published By: National Institutes of Health


