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Learn About Sideroblastic Anemia

View Main Condition: Anemia

What is the definition of Sideroblastic Anemia?
Sideroblastic anemia is a group of blood disorders characterized by an impaired ability of the bone marrow to produce normal red blood cells. In this condition, the iron inside red blood cells is inadequately used to make hemoglobin, despite normal amounts of iron. As a result, iron accumulates in the red blood cells, giving a ringed appearance to the nucleus (ringed sideroblast). The signs and symptoms of this condition may include fatigue, breathing difficulties, weakness, and enlargement of the liver or spleen. There are many potential causes of Sideroblastic anemia. Depending on the cause, it can be classified as hereditary (sometimes called congenital), acquired, and idiopathic (cause unknown).
What are the alternative names for Sideroblastic Anemia?
  • Sideroblastic anemia
  • Anemia sideroblastic
Who are the top Sideroblastic Anemia Local Doctors?
Amy Dezern
Elite in Sideroblastic Anemia
Oncology | Hematology
Elite in Sideroblastic Anemia
Oncology | Hematology

Sidney Kimmel Comprehensive Cancer Center

401 North Broadway Street, Weinberg BLDG, Weinberg BLDG, 
Baltimore, MD 
Languages Spoken:
English
Offers Telehealth

Dr. DeZern is a Professor of Oncology and Medicine at The Johns Hopkins University School of Medicine. She is active in the Division of Hematology Malignancies, Leukemia Program at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Dr. DeZern has expertise in aplastic anemia, myelodysplastic syndromes, paroxysmal nocturnal hemoglobinuria, acute myeloid leukemia, and bone marrow transplantation. Dr. DeZern received her medical degree at The Johns Hopkins University School of Medicine. She completed a residency in internal medicine at Johns Hopkins, followed by fellowships in medical oncology and hematology, as well as obtained a Masters in Clinical Investigations at the Bloomberg School of Public health. Dr. DeZern is a member of the American Society of Hematology, the American Society of Clinical Oncology, and the American Society for Transplantation and Cellular Therapy. Dr. DeZern’s principle research activities consist of designing and conducting clinical trials that test investigational new therapies and approaches in the treatment of bone marrow failure (aplastic anemia and myelodysplastic syndromes). She has specific expertise in the use of alternative donor bone marrow transplantation in patients with severe aplastic anemia and trials of novel therapeutics for patients with myelodysplastic syndromes. Additionally, she has taken a rigorous approach to the study of diagnostics and supportive case (such as transfusion practices) in these patient populations. She is or has been the Principal Investigator for a number of multicenter trials in collaboration with the MDS Clinical Research Consortium, the Eastern Co-operative Oncology Group (ECOG)-ACRIN and now the Bone Marrow Trials Clinical Trials Network (BMTCTN). She is the Study Chair for the multi-site BMTCTN study (CHAMP) investigating the role of haploidentical donor transplantation using post-transplantation cyclophosphamide in patients with relapsed several aplastic anemia. Dr. DeZern is the local PI as well as the Deputy Chair for The National MDS Study, a collaborative natural history study of the NHLBI and the NCI. As a clinical investigator with a focus on translation of novel treatments to the clinic, Dr. DeZern’s goal is to improve outcomes for patients with bone marrow failure at the bedside and in her research environment. Dr. Dezern is rated as an Elite provider by MediFind in the treatment of Sideroblastic Anemia. Her top areas of expertise are Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), Acute Myeloid Leukemia (AML), Bone Marrow Transplant, and Bone Marrow Aspiration.

Carlos M. De Castro Iii
Advanced in Sideroblastic Anemia
Hematology Oncology | Hematology
Advanced in Sideroblastic Anemia
Hematology Oncology | Hematology

Duke Blood Cancer Center

2400 Pratt St, 
Durham, NC 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Carlos De Castro Iii is a Hematologist Oncology specialist and a Hematologist in Durham, North Carolina. Dr. De Castro Iii is rated as an Advanced provider by MediFind in the treatment of Sideroblastic Anemia. His top areas of expertise are Paroxysmal Nocturnal Hemoglobinuria (PNH), Aplastic Anemia, Acute Myeloblastic Leukemia without Maturation, Acute Myeloid Leukemia (AML), and Bone Marrow Aspiration. Dr. De Castro Iii is currently accepting new patients.

 
 
 
 
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Elite in Sideroblastic Anemia
Elite in Sideroblastic Anemia
Sendai, JP 

Hideo Harigae practices in Sendai, Japan. Mr. Harigae is rated as an Elite expert by MediFind in the treatment of Sideroblastic Anemia. His top areas of expertise are Sideroblastic Anemia, Follicular Lymphoma, Anemia, Bone Marrow Transplant, and Angioplasty.

What are the latest Sideroblastic Anemia Clinical Trials?
A Retrospective/Prospective, Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs) With Clinical Significance.

Summary: Rare Anaemia Disorders (RADs) is a group of rare diseases characterized for presenting anaemia as the main clinical manifestation. Different medical entities classified as RADs by ORPHA classification are most of them chronic life threating disorders with many unmet needs for their proper clinical management creating an impact on European health systems. RADs present diagnostic challenges and thei...

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Published Date: May 06, 2022
Published By: Genetic and Rare Diseases Informnation Center