Sjogren SyndromeSymptoms, Doctors, Treatments, Advances & More
Learn About Sjogren Syndrome
Sjögren syndrome is a disorder whose main features are dry eyes and a dry mouth. The condition typically develops gradually beginning in middle adulthood but can occur at any age.
Sjögren syndrome is thought to result from a combination of genetic and environmental factors; however, no associations between specific genetic changes and the development of Sjögren syndrome have been confirmed. Researchers believe that variations in many genes affect the risk of developing Sjögren syndrome, but that development of the condition may be triggered by something in the environment. In particular, viral or bacterial infections, which activate the immune system, may have the potential to encourage the development of Sjögren syndrome in susceptible individuals. The genetic variations that increase susceptibility may reduce the body's ability to turn off the immune response when it is no longer needed.
Sjögren syndrome is a relatively common disorder; it occurs in 0.1 to 1 percent of the population. It is difficult to determine the exact prevalence because the characteristic features of this disorder, dry eyes and dry mouth, can also be caused by many other conditions. Women develop Sjögren syndrome about 10 times more often than men; the specific reason for this difference is unknown but likely involves the effects of sex hormones on immune system function.
A predisposition to develop autoimmune disorders can be passed through generations in families. Relatives of people with Sjögren syndrome are at an increased risk of developing autoimmune diseases, although they are not necessarily more likely to develop Sjögren syndrome in particular. The inheritance pattern of this predisposition is unknown.
Johns Hopkins Bayview Medical Center
Alan Baer is a Rheumatologist practicing medicine in Baltimore, Maryland. Dr. Baer is rated as an Elite provider by MediFind in the treatment of Sjogren Syndrome. He is also highly rated in 11 other conditions, according to our data. His clinical expertise encompasses Sjogren Syndrome, Rheumatoid Arthritis (RA), Arthritis, and Interstitial Keratitis. Dr. Baer is board certified in American Board Of Internal Medicine. Dr. Baer is currently accepting new patients.
Junction Rd Medical Center Rheumatology Clinic
Sara Mccoy is a Rheumatologist practicing medicine in Madison, Wisconsin. Dr. Mccoy is rated as an Elite provider by MediFind in the treatment of Sjogren Syndrome. She is also highly rated in 8 other conditions, according to our data. Her clinical expertise encompasses Sjogren Syndrome, Rheumatoid Arthritis (RA), Arthritis, and Scleroderma. Dr. Mccoy is board certified in Rheumatology and Internal Medicine. Dr. Mccoy is currently accepting new patients.
Presbyterian Multi-Specialty Group
Frederick Vivino is a Rheumatologist practicing medicine in Philadelphia, Pennsylvania. Dr. Vivino is rated as an Elite provider by MediFind in the treatment of Sjogren Syndrome. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Sjogren Syndrome, Interstitial Keratitis, Rheumatoid Arthritis (RA), and Arthritis. Dr. Vivino is currently accepting new patients.
Background: \- Salivary glands in and around the mouth and throat make saliva. Salivary gland disorders can affect a person s quality of life. Studying people who have a disease that affects their salivary gland(s) may teach researchers about the disorders and their genetics.
Background: -Sjogren s Disease (formerly: Sjogrens Syndrome, Sj(SqrRoot)(Delta)gren s syndrome) is a disease that affects about 1-4 million Americans. It is more common in women. It mainly affects the glands that produce saliva and tears, leading to dry eyes and dry mouth. The cause of Sjogren s Disease is unknown, but inflammation plays an important role. The purpose of this study is to learn more about Sjog...
Published Date: December 09, 2021
Published By: National Institutes of Health