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Evaluation of Diagnostic Value of 18F-T2 PET/ CT Imaging for Tumors Likely to Express High Levels of CAIX

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to evaluate the diagnostic value of CAIX protein specific probe 18F-T2 in PET/CT imaging in participants with solid tumors. It will also assess the safety, tolerability and radiation dosimetry of 18F-T2.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
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⁃ All participants must meet the following criteria:

• Written and voluntarily given Informed Consent.

• Male or female ≥18 years of age at time of consent.

• Have the capacity to understand the study and be willing and able to comply with all protocol requirements.

• Participants with histologically confirmed or suspected tumors of the following types, but not limited to:

⁃ Clear Cell Renal Cell Cancer; Urothelial Carcinoma; Colorectal Cancer; Cervical Cancer; Ovarian Cancer; Head and Neck Cancer; Hepatocellular Carcinoma; Cholangiocarcinoma; Non Small Cell Lung Cancer; Small Cell Lung Cancer; Breast Cancer; Pancreatic Cancer; Endometrial Cancer; Von Hippel Lindau Disease.

Locations
Other Locations
China
Peking University First Hospital
RECRUITING
Beijing
Contact Information
Primary
Keting Tong
1910301229@pku.edu.cn
+86 010-83575252
Time Frame
Start Date: 2026-04-27
Estimated Completion Date: 2029-03
Participants
Target number of participants: 200
Treatments
Experimental: 18F-T2 PET/CT
Participants with tumors likely to express high levels of CAIX will receive an intravenous injection of 18F-T2 followed by PET/CT imaging. The participants will also receive a whole-body 18F-FDG PET/CT scan within a one-week period.
Sponsors
Leads: Peking University First Hospital

This content was sourced from clinicaltrials.gov