Spastic Paraplegia Type 2 Latest Advances

Pearls & Oy-sters: Hereditary Spastic Paraplegia Type 15 Presenting as Juvenile Onset Levodopa-Responsive Parkinsonism.

Journal: Neurology

Published: January 08, 2026

Fampridine in Hereditary Spastic Paraplegia Type 4 With SPAST Variant c.683-2A>C: A Case Report.

Journal: The American journal of case reports

Published: January 07, 2026

Basic Science and Pathogenesis.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: December 29, 2025

DDHD2 possesses both lipase and transacylase capacities that remodel triglyceride acyl chains.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 20, 2025

Novel MTHFR variants manifesting with hereditary spastic paraplegia and recurrent pulmonary embolism: a case report and literature review of adult-onset severe MTHFR deficiency.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Published: November 13, 2025

Clinical characteristics and genetic study of a child with Spastic paraplegia 52 due to variant of AP4S1 gene and a literature review

Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

Published: November 13, 2025

Neurodevelopmental disorders in childhood-onset hereditary spastic paraplegia type 7: a case series and review of literature.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Published: November 04, 2025

Nutritional Approaches in Neurodegenerative Disorders: A Mini Scoping Review with Emphasis on SPG11-Related Conditions.

Journal: Nutrients

Published: September 24, 2025

Diagnostic Yield and Genotype-Phenotype Correlations of Clinical Exome Sequencing in Hereditary Spastic Paraparesis: Experience From Eastern Spain.

Journal: European journal of neurology

Published: September 23, 2025

Botulinum Toxin Treatment in Hereditary Spastic Paraplegia-A Comprehensive Review and Update.

Journal: Toxins

Published: September 04, 2025

Miglustat does not impact clinical progression in patients with spastic paraplegia type 11.

Journal: Neurogenetics

Published: August 28, 2025

The Impact of VAMP1 Mutations on Synaptic Vesicle Fusion Dynamics in Familial Spastic Disorders.

Journal: Journal of child neurology

Published: August 26, 2025