Comparison Study of Conventional Peroral Endoscopic Myotomy (POEM) and Different Modified Procedures of POEM for Achalasia

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aims of this study are 1) to compare the efficacy and safety of conventional myotomy (long myotomy) and modified myotomy (short myotomy) in the treatment of type I/II achalasia patients diagnosed according to Chicago Classification; 2) to compare the efficacy and safety of conventional myotomy (circular myotomy) and modified myotomy (full-thickness myotomy) in the treatment of type I/II achalasia patients; 3) to compare the efficacy and safety of conventional myotomy (non-tailored myotomy) and modified myotomy (tailored myotomy) in the treatment of type III achalasia patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 14
Maximum Age: 70
Healthy Volunteers: f
View:

• Subjects diagnosed as achalasia type I, II, or III on the basis of the results of established methods (barium swallow, manometry, esophagogastroduodenoscopy)

• Candidate for a POEM

• No contra-indication to general anesthesia

• Their age is ≥14years and ≤70 years

• Able to give written consent

Locations
Other Locations
China
Department of Gastroenterology, Peking Union Medical College Hospital
RECRUITING
Beijing
Contact Information
Primary
Tao Guo, MD
guoqiong990@126.com
8610-69155017
Time Frame
Start Date: 2020-09-02
Estimated Completion Date: 2026-05-30
Participants
Target number of participants: 325
Treatments
Active_comparator: conventional myotomy
conventional myotomy for achalasia type I, II and III
Experimental: short myotomy
modified myotomy (short myotomy) for achalasia type I and II
Experimental: full-thickness myotomy
modified myotomy (full-thickness myotomy) for achalasia type I and II
Experimental: tailored myotomy
modified myotomy (tailored myotomy) for achalasia type III
Related Therapeutic Areas
Sponsors
Leads: Peking Union Medical College Hospital

This content was sourced from clinicaltrials.gov

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