Spinocerebellar Ataxia Type 2 Latest Advances

Genomic Organization, Evolutionary Conservation and Expression of Ataxin-2 and Ataxin-2-like Genes Underscore the Suitability of Zebrafish as a Model Organism for SCA2 and Related Diseases.

Journal: Biomedicines

Published: November 12, 2025

Progression of Gait Ataxia in Spinocerebellar Ataxia Type 2: Clinical Utility of Digitally Measured Gait Metrics.

Journal: Cerebellum (London, England)

Published: August 27, 2025

Deep Learning-Based Assessment of Brainstem Volume Changes in Spinocerebellar Ataxia Type 2 (SCA2): A Study on Patients and Preclinical Subjects.

Journal: Sensors (Basel, Switzerland)

Published: July 12, 2025

Cognitive Deficits in Spinocerebellar Ataxia Type 2: A Comparative Analysis of Pre-ataxic and Ataxic Stages.

Journal: Cerebellum (London, England)

Published: June 24, 2025

Correlation Networks To Uncover Changes in Protein Relationships in Spinocerebellar Ataxia Type 2 and Cerebellar Multiple System Atrophy.

Journal: Journal of proteome research

Published: June 18, 2025

Elevated Interleukin-8 in Spinocerebellar Ataxia Type 2: A Distinct Peripheral Immune Signature Unrelated To Disease Severity.

Journal: Cerebellum (London, England)

Published: June 18, 2025

Multiomics approach identifies SERPINB1 as candidate biomarker for spinocerebellar ataxia type 2.

Journal: Scientific reports

Published: May 27, 2025

Identifying Molecular Properties of Ataxin-2 Inhibitors for Spinocerebellar Ataxia Type 2 Utilizing High-Throughput Screening and Machine Learning.

Journal: Biology

Published: April 21, 2025

Spinal Cord Phosphoproteome of SCA2 Mouse Model Reveals Alteration of ATXN2-N-Term PRM-SH3-Actin Interactome and of Autophagy.

Journal: Molecular & cellular proteomics : MCP

Published: April 21, 2025

Respiratory Evaluation in Spinocerebellar ataxia Type 2.

Journal: Cerebellum (London, England)

Published: April 21, 2025

Spinocerebellar ataxia type 2 followed by amyotrophic lateral sclerosis due to a pure CAG repeat expansion in ATXN2: a case report and literature review.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Published: April 02, 2025

The Two Faces of Pediatric SCA2.

Journal: European journal of neurology

Published: March 05, 2025