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Learn About Spinocerebellar Ataxia Type 3

View Main Condition: Movement Disorders

What is the definition of Spinocerebellar Ataxia Type 3?
Spinocerebellar ataxia 3 (SCA3) is a rare, inherited form of ataxia. Signs and symptoms may begin between childhood and late adulthood and vary greatly. Symptoms may include slowly progressive clumsiness in the arms and legs; a manner of walking (gait) that may be mistaken for drunkenness; difficulty speaking and swallowing; impaired eye movements or vision; and lower limb spasticity. Some people with SCA3 develop dystonia or symptoms similar to those of Parkinson's disease; twitching of the face or tongue; nerve damage (neuropathy); or problems with urination and the autonomic nervous system. SCA3 is caused by a genetic change in the ATXN3 gene and inheritance is autosomal dominant.
What are the alternative names for Spinocerebellar Ataxia Type 3?
  • Spinocerebellar ataxia 3
  • Azorean neurologic disease
  • MJD
  • Machado-Joseph disease
  • Nigrospinodentatal degeneration
  • SCA3
  • Spinocerebellar atrophy type 3
  • Spinopontine atrophy
Who are the top Spinocerebellar Ataxia Type 3 Local Doctors?
Elite in Spinocerebellar Ataxia Type 3
Elite in Spinocerebellar Ataxia Type 3
Sao Paulo, SP, BR 

Jose Pedroso practices in Sao Paulo, Brazil. Mr. Pedroso is rated as an Elite expert by MediFind in the treatment of Spinocerebellar Ataxia Type 3. His top areas of expertise are Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia, Olivopontocerebellar Atrophy, and Drug Induced Dyskinesia.

Elite in Spinocerebellar Ataxia Type 3
Elite in Spinocerebellar Ataxia Type 3
Braga, PT 

Patricia Maciel practices in Braga, Portugal. Ms. Maciel is rated as an Elite expert by MediFind in the treatment of Spinocerebellar Ataxia Type 3. Her top areas of expertise are Spinocerebellar Ataxia Type 3, Olivopontocerebellar Atrophy, Spinocerebellar Ataxia, and Striatonigral Degeneration Infantile.

 
 
 
 
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Elite in Spinocerebellar Ataxia Type 3
Elite in Spinocerebellar Ataxia Type 3

Regents Of The University Of Michigan

4260 Plymouth Rd, U Of M Sleep Medicine, 
Ann Arbor, MI 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Henry Paulson is a Neurologist in Ann Arbor, Michigan. Dr. Paulson is rated as an Elite provider by MediFind in the treatment of Spinocerebellar Ataxia Type 3. His top areas of expertise are Olivopontocerebellar Atrophy, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia, and Drug Induced Dyskinesia. Dr. Paulson is currently accepting new patients.

What are the latest Spinocerebellar Ataxia Type 3 Clinical Trials?
A Phase 1/2a, Open-label Trial to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of Intrathecally Administered VO659 in Participants With Spinocerebellar Ataxia Types 1, 3 and Huntington's Disease

Summary: The goal of this first-in-human clinical trial is to assess the safety and tolerability of four doses of a new study drug called VO659 in people with genetic disorders called spinocerebellar ataxia type 1, type 3 or Huntington's disease. Another aim is to determine the concentrations of the study drug in the cerebral spinal fluid and blood after single and multiple doses. Study drug will be admini...

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Coordination of Rare Diseases at Sanford

Summary: CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, in...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

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