Spinocerebellar Ataxia Type 4 Symptoms, Doctors, Treatments, Advances & More

Learn About Spinocerebellar Ataxia Type 4

What is the definition of Spinocerebellar Ataxia Type 4?

Spinocerebellar ataxia 4 (SCA4) is a very rare form of hereditary progressive movement disorder. Symptoms include muscle weakness (atrophy) and difficulty coordinating body movements (ataxia), most notably causing a jerky, unsteady walking style (gait) and difficulty speaking (dysarthria). A distinctive feature of SCA4 is the progressive loss of feeling or sensation in the hands and feet (peripheral neuropathy) and loss of reflexes. SCA4 is inherited in an autosomal dominant manner. Although SCA4 has been linked to a location on chromosome 16, (16q22.1), the gene which causes SCA4 when mutated has not been found. Diagnosis is based on symptoms consistent with the disease.

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What are the alternative names for Spinocerebellar Ataxia Type 4?

Spinocerebellar ataxia 4
SCA4
Spinocerebellar ataxia autosomal dominant with sensory axonal neuropathy
Spinocerebellar ataxia type 4

Who are the top Spinocerebellar Ataxia Type 4 Local Doctors?

Alexandra M. Durr

Elite

Highly rated in

conditions

Pitié-Salpêtrière Hospital

Paris, FR

Alexandra Durr practices in Paris, France. Durr is rated as an Elite expert by MediFind in the treatment of Spinocerebellar Ataxia Type 4. She is also highly rated in 54 other conditions, according to our data. Her top areas of expertise are Huntington Disease, Spinocerebellar Ataxia, Drug Induced Dyskinesia, and Olivopontocerebellar Atrophy.

Dr. Tetsuo Ashizawa

Neurology | Nephrology

Elite

Highly rated in

conditions

Neurology
Nephrology

Houston Methodist

Houston Methodist Department Of Neurology - TMC Suite 802

6560 Fannin St,

Houston, TX

Tetsuo Ashizawa is a Neurologist and a Nephrologist in Houston, Texas. Ashizawa has been practicing medicine for over 50 years and is rated as an Elite expert by MediFind in the treatment of Spinocerebellar Ataxia Type 4. He is also highly rated in 36 other conditions, according to our data. His top areas of expertise are Olivopontocerebellar Atrophy, Spinocerebellar Ataxia, Spinocerebellar Ataxia Type 10, Drug Induced Dyskinesia, and Deep Brain Stimulation. He is licensed to treat patients in Florida and Texas. Ashizawa is currently accepting new patients.

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Luis C. Perez-Velazquez

Elite

Highly rated in

conditions

Centre For The Research And Rehabilitation Of Hereditary Ataxias

Lenin Avenue 1,

Holguin, CU

Luis Perez-Velazquez practices in Holguin, Cuba. Perez-Velazquez is rated as an Elite expert by MediFind in the treatment of Spinocerebellar Ataxia Type 4. He is also highly rated in 19 other conditions, according to our data. His top areas of expertise are Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 7, Spinocerebellar Ataxia Type 6, and Spinocerebellar Ataxia Type 5.

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What are the latest Spinocerebellar Ataxia Type 4 Clinical Trials?

Using Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback and Motor Imagery to Enhance Motor Timing and Precision in Cerebellar Ataxia

Enrollment Status: Recruiting

Publish Date: December 13, 2022

Intervention Type: Behavioral, Device

Study Phase: Not Applicable

Summary: The aim of the research is to improve motor function in people with cerebellar ataxia by using neuroimaging methods and mental imagery to exercise motor networks in the brain. The relevance of this research to public health is that results have the potential to reduce motor deficits associated with cerebellar atrophy, thereby enhancing the quality of life and promoting independence.

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A Phase 1, Blinded, Randomized, Placebo-controlled Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of BIIB132 Administered Intrathecally to Adults With Spinocerebellar Ataxia 3

Who is this study for: Adults with spinocerebellar ataxia type 3

Enrollment Status: Recruiting

Publish Date: December 12, 2022

Intervention Type: Drug

Study Drug: BIIB132

Study Phase: Phase 1

Summary: The primary objective of this study is to evaluate the safety and tolerability of multiple ascending doses of BIIB132 administered via intrathecal (IT) injection to participants with spinocerebellar ataxia type 3 (SCA3). The secondary objective of this study is to characterize the multiple-dose pharmacokinetics (PK) of BIIB132 administered via IT injection to participants with SCA3.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Spinocerebellar Ataxia Type 4?