Learn About Splenomegaly

What is the definition of Splenomegaly?

Splenomegaly is a larger-than-normal spleen. The spleen is an organ in the upper left part of the belly.

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What are the alternative names for Splenomegaly?

Spleen enlargement; Enlarged spleen; Spleen swelling

What is some background information about Splenomegaly?

The spleen is an organ that is a part of the lymph system. The spleen filters the blood and maintains healthy red and white blood cells and platelets. It also plays a role in immune function.

Many health conditions can affect the spleen. These include:

  • Diseases of the blood or lymph system
  • Infections
  • Cancer
  • Liver disease

Symptoms of splenomegaly include:

  • Hiccups
  • Inability to eat a large meal
  • Pain in the upper left side of the belly
What are the causes of Splenomegaly?

Splenomegaly can be caused by any of the following:

  • Infections
  • Liver diseases
  • Blood diseases
  • Cancer
How do I perform a home exam for a Splenomegaly?

In rare cases, an injury can rupture the spleen. If you have splenomegaly, your health care provider may advise you to avoid contact sports. Your provider will tell you what else you need to do to take care of yourself and any medical condition.

When should I contact a medical professional for Splenomegaly?

There are usually no symptoms from an enlarged spleen. Seek medical help right away if pain in your belly is severe or gets worse when you take a deep breath.

What should I expect during a doctor appointment?

The provider will ask about your symptoms and medical history.

A physical exam will be done. The provider will feel and tap along the upper left part of your belly, especially just under the rib cage.

Tests that may be done include:

  • Abdominal x-ray, ultrasound, or CT scan
  • Blood tests, such as a complete blood count (CBC) and tests of your liver function

Treatment depends on the cause of splenomegaly.

Splenomegaly
Enlarged spleen
Who are the top Splenomegaly Local Doctors?
Elite
Highly rated in
29
conditions
Oncology
Hematology Oncology

University of Texas System

Physicians Referral Service

1515 Holcombe Blvd 
Houston, TX 77030

Srdan Verstovsek is an Oncologist and a Hematologist Oncology doctor in Houston, Texas. Dr. Verstovsek has been practicing medicine for over 30 years and is rated as an Elite doctor by MediFind in the treatment of Splenomegaly. He is also highly rated in 29 other conditions, according to our data. His top areas of expertise are Myelofibrosis, Myeloproliferative Neoplasms, Splenomegaly, and Essential Thrombocythemia. He is licensed to treat patients in Texas. Dr. Verstovsek is currently accepting new patients.

Elite
Highly rated in
19
conditions
Oncology
Hematology Oncology
Hematology

Beaumont Health System

Mays Cancer Center

7979 Wurzbach Rd 
San Antonio, TX 78229

Ruben Mesa is an Oncologist and a Hematologist Oncology doctor in San Antonio, Texas. Dr. Mesa has been practicing medicine for over 27 years and is rated as an Elite doctor by MediFind in the treatment of Splenomegaly. He is also highly rated in 19 other conditions, according to our data. His top areas of expertise are Myelofibrosis, Polycythemia Vera, Essential Thrombocythemia, and Myeloproliferative Neoplasms. He is licensed to treat patients in Minnesota, Texas, and Arizona. Dr. Mesa is currently accepting new patients.

 
 
 
 
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Elite
Highly rated in
15
conditions

Guy's And St Thomas' NHS Foundation Trust

London, ENG, GB 

Claire Harrison is in London, United Kingdom. Harrison is rated as an Elite expert by MediFind in the treatment of Splenomegaly. She is also highly rated in 15 other conditions, according to our data. Her top areas of expertise are Essential Thrombocythemia, Myelofibrosis, Myeloproliferative Neoplasms, and Polycythemia Vera.

What are the latest Splenomegaly Clinical Trials?
An Observational National Pediatric Study on Prevalence of Unexplained Splenomegaly
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A Phase 2/3, Multicenter, Randomized, Double-blinded, Placebo-controlled, Repeat-dose Study to Evaluate the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency
What are the Latest Advances for Splenomegaly?
Rare case of littoral cell angioma recognised on CT simulation for adjuvant radiation treatment for early stage breast cancer.
Tumor Flare Reaction in a Classic Hodgkin Lymphoma Patient Treated With Brentuximab Vedotin and Tislelizumab: A Case Report.
Tired of the same old research?
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Secondary Hemophagocytic Lymphohistiocytosis in a Neonate with SARS-CoV-2 Infection.
Who are the sources who wrote this article ?

Published Date : February 06, 2020
Published By : Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Winter JN. Approach to the patient with lymphadenopathy and splenomegaly. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 159.

Vos PM, Barnard SA, Cooperberg PL. Benign and malignant lesions of the spleen. In: Gore RM, Levine MS, eds. Textbook of Gastrointestinal Radiology. 4th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 105.

Vos PM, Mathieson JR, Cooperberg PL. The spleen. In: Rumack CM, Levine D, eds. Diagnostic Ultrasound. 5th ed. Philadelphia, PA: Elsevier; 2018:chap 5.