Splenomegaly is a larger-than-normal spleen. The spleen is an organ in the upper left part of the belly.
Spleen enlargement; Enlarged spleen; Spleen swelling
The spleen is an organ that is a part of the lymph system. The spleen filters the blood and maintains healthy red and white blood cells and platelets. It also plays a role in immune function.
Many health conditions can affect the spleen. These include:
Symptoms of splenomegaly include:
Splenomegaly can be caused by any of the following:
In rare cases, an injury can rupture the spleen. If you have splenomegaly, your health care provider may advise you to avoid contact sports. Your provider will tell you what else you need to do to take care of yourself and any medical condition.
There are usually no symptoms from an enlarged spleen. Seek medical help right away if pain in your belly is severe or gets worse when you take a deep breath.
The provider will ask about your symptoms and medical history.
A physical exam will be done. The provider will feel and tap along the upper left part of your belly, especially just under the rib cage.
Tests that may be done include:
Treatment depends on the cause of splenomegaly.
Rajeev Khanna is an Internal Medicine doctor in Herndon, Virginia. Dr. Khanna has been practicing medicine for over 38 years and is rated as a Distinguished doctor by MediFind in the treatment of Splenomegaly. He is also highly rated in 21 other conditions, according to our data. His top areas of expertise are Hepatocerebral Degeneration, Liver Failure, Wilson Disease, Liver Transplant, and Cardiac Ablation. Dr. Khanna is currently accepting new patients.
Venkateswar Veerapalli is an Oncologist and a Hematologist Oncology doctor in Ashburn, Virginia. Dr. Veerapalli has been practicing medicine for over 34 years and is rated as an Experienced doctor by MediFind in the treatment of Splenomegaly. He is also highly rated in 27 other conditions, according to our data. His top areas of expertise are Follicular Lymphoma, Hemochromatosis, Leukocytosis, and Hemosiderosis. Dr. Veerapalli is currently accepting new patients.
Ajay Dar is an Oncologist and a Hematologist in Reston, Virginia. Dr. Dar has been practicing medicine for over 39 years and is rated as an Experienced doctor by MediFind in the treatment of Splenomegaly. He is also highly rated in 14 other conditions, according to our data. His top areas of expertise are Ovarian Carcinosarcoma, Ovarian Cancer, Testicular Yolk Sac Tumor, and Sertoli-Leydig Cell Tumor. Dr. Dar is currently accepting new patients.
Summary: The thalassemias are a group of inherited hematologic disorders caused by defects in the synthesis of one or more of the hemoglobin chains [1]. Thalassemia are classified into the alpha (α) and (β) thalassemia, which contain deficits in (α) and (β) globin production respectively (α)thalassemia are caused by decreased production of alpha-globin chains from chromosome 16. There are 4 types of (α) th...
Summary: Myelofibrosis (MF) is a bone marrow illness that affects blood-forming tissues in the body. MF disturbs the body's normal production of blood cells, causing extensive scarring in the bone marrow. This leads to severe anemia, weakness, fatigue, and an enlarged spleen. The purpose of this study is to see how safe and tolerable ABBV-744 is, when given alone, and in combination with ruxolitinib or nav...
Published Date: January 25, 2022
Published By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Vos PM, Barnard SA, Cooperberg PL. Benign and malignant lesions of the spleen. In: Gore RM, Levine MS, eds. Textbook of Gastrointestinal Radiology. 4th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 105.
Vos PM, Mathieson JR, Cooperberg PL. The spleen. In: Rumack CM, Levine D, eds. Diagnostic Ultrasound. 5th ed. Philadelphia, PA: Elsevier; 2018:chap 5.
Winter JN. Approach to the patient with lymphadenopathy and splenomegaly. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 159.