Learn About Splenomegaly

CONSIDERATIONS

The spleen is an organ that is a part of the lymph system. The spleen filters the blood and maintains healthy red and white blood cells and platelets. It also plays a role in immune function.

Many health conditions can affect the spleen. These include:

  • Diseases of the blood or lymph system
  • Infections
  • Cancer
  • Liver disease

Symptoms of splenomegaly include:

  • Hiccups
  • Inability to eat a large meal
  • Pain in the upper left side of the belly
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In rare cases, an injury can rupture the spleen. If you have splenomegaly, your health care provider may advise you to avoid contact sports. Your provider will tell you what else you need to do to take care of yourself and any medical condition.

WHAT TO EXPECT AT YOUR OFFICE VISIT

The provider will ask about your symptoms and medical history.

A physical exam will be done. The provider will feel and tap along the upper left part of your belly, especially just under the rib cage.

Tests that may be done include:

  • Abdominal x-ray, ultrasound, or CT scan
  • Blood tests, such as a complete blood count (CBC) and tests of your liver function

Treatment depends on the cause of splenomegaly.

Splenomegaly
Enlarged spleen
What is the definition of Splenomegaly?

Splenomegaly is a larger-than-normal spleen. The spleen is an organ in the upper left part of the belly.

What are the alternative names for Splenomegaly?

Spleen enlargement; Enlarged spleen; Spleen swelling

What are the causes of Splenomegaly?

Splenomegaly can be caused by any of the following:

  • Infections
  • Liver diseases
  • Blood diseases
  • Cancer
When should I contact a medical professional for Splenomegaly?

There are usually no symptoms from an enlarged spleen. Seek medical help right away if pain in your belly is severe or gets worse when you take a deep breath.

Who are the top Splenomegaly Local Doctors?
Elite
Highly rated in
15
conditions
Orthopedics

Palmetto Health-USC Orthopedic Center

Columbia, SC 

Gregory Grabowski is an Orthopedics doctor in Columbia, South Carolina. Dr. Grabowski has been practicing medicine for over 17 years and is rated as an Elite doctor by MediFind in the treatment of Splenomegaly. He is also highly rated in 15 other conditions, according to our data. His top areas of expertise are Gaucher Disease, Gaucher Disease Type 1, Gaucher Disease Type 3, and Gaucher Disease Type 2. He is board certified in Orthopedic Surgery and licensed to treat patients in South Carolina. Dr. Grabowski is currently accepting new patients.

Elite
Highly rated in
26
conditions
Oncology
Hematology Oncology

University Of Texas MD Anderson Cancer Center

Houston, TX 

Srdan Verstovsek is an Oncologist and a Hematologist Oncology doctor in Houston, Texas. Dr. Verstovsek has been practicing medicine for over 30 years and is rated as an Elite doctor by MediFind in the treatment of Splenomegaly. He is also highly rated in 26 other conditions, according to our data. His top areas of expertise are Myelofibrosis, Splenomegaly, Essential Thrombocythemia, and Polycythemia Vera. He is board certified in Medical Oncology, Hematology/oncology, and Internal Medicine and licensed to treat patients in Texas. Dr. Verstovsek is currently accepting new patients.

 
 
 
 
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Elite
Highly rated in
19
conditions
Oncology
Hematology Oncology
Hematology

Mays Cancer Center

San Antonio, TX 

Ruben Mesa is an Oncologist and a Hematologist Oncology doctor in San Antonio, Texas. Dr. Mesa has been practicing medicine for over 27 years and is rated as an Elite doctor by MediFind in the treatment of Splenomegaly. He is also highly rated in 19 other conditions, according to our data. His top areas of expertise are Myelofibrosis, Polycythemia Vera, Essential Thrombocythemia, and Splenomegaly. He is board certified in Medical Oncology and Hematology and licensed to treat patients in Texas, Minnesota, and Arizona. Dr. Mesa is currently accepting new patients.

What are the latest Splenomegaly Clinical Trials?
Construction and Evaluation of the Early Identification for Oxaliplatin Induced Portal Hypertension
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A Phase 1b Study Of ABBV-744 Alone Or In Combination With Ruxolitinib Or Navitoclax In Subjects With Myelofibrosis
What are the Latest Advances for Splenomegaly?
Splenectomy for the treatment of common variable immunodeficiency complicated with cytopenia: report of one case and literature review.
Atypical Chronic Myeloid Leukemia: New Developments from Molecular Diagnosis to Treatment.
Tired of the same old research?
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A Case of Chronic Q Fever Endocarditis Mimicking Lymphoproliferative Disorders.
What are our references for Splenomegaly?

Winter JN. Approach to the patient with lymphadenopathy and splenomegaly. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 159.

Vos PM, Barnard SA, Cooperberg PL. Benign and malignant lesions of the spleen. In: Gore RM, Levine MS, eds. Textbook of Gastrointestinal Radiology. 4th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 105.

Vos PM, Mathieson JR, Cooperberg PL. The spleen. In: Rumack CM, Levine D, eds. Diagnostic Ultrasound. 5th ed. Philadelphia, PA: Elsevier; 2018:chap 5.