Learn About Squamous Cell Skin Carcinoma

What is the definition of Squamous Cell Skin Carcinoma?
Squamous cell skin carcinoma is a type of skin cancer that most often appears on areas of the skin exposed to the sun, such as the scalp, ears, lips, and backs of hands. Squamous cell skin carcinoma can also appear inside the mouth, on the genitals, and on the underside of the feet.
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What are the symptoms of Squamous Cell Skin Carcinoma?
Symptoms of squamous cell skin carcinoma include the appearance on the skin of a firm, red nodule or a flat sore with a scaly crust; a new sore on an old scar; a rough scaly patch on the lip that progresses to an open sore; a red sore or rough patch inside the mouth; or a red, raised patch or sore that looks like a wart on the genitals or the anus.
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What are the current treatments for Squamous Cell Skin Carcinoma?
Treatments for squamous cell skin carcinoma depend on the area affected and whether the tumor has spread. Treatments for squamous cell skin carcinoma of the skin may include surgery; photodynamic therapy; chemotherapy; radiation therapy; targeted drug therapy; immunotherapy; such as cemiplimab-rwlc; and palliative therapy.
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What are the latest Squamous Cell Skin Carcinoma Clinical Trials?
Phase I Study of MEM-288 Oncolytic Virus in Solid Tumors Including Non-Small Cell Lung Cancer (NSCLC)

Summary: This phase I trial is designed as an open-label, dose escalation trial of MEM-288 monotherapy in which investigators aim to find the maximum tolerated dose (MTD) and recommended phase II dose (RP2D). Subjects with selected solid tumors including non-small cell lung cancer (NSCLC) who have a tumor lesion which is accessible for injection will undergo intratumoral injection of MEM-288. The study rat...

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Open Label Phase 2 Study of Tisotumab Vedotin for Locally Advanced or Metastatic Disease in Solid Tumors

Summary: This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted effects) may occur. There are four parts to this study. In Part A, the treatment will be given to participants every 3 weeks (3-week cycles). In Part B, participants will receive tisotumab vedotin on Days 1, 8, and 15 every 4-week cycle. In Part C, parti...

What are the Latest Advances for Squamous Cell Skin Carcinoma?
Anal cancer with isolated ischial fossa lymph node metastases: A rare entity in the oligometastatic dilemma.
Application of transverse cervical artery flap in laryngeal function preservation surgery of hypopharyngeal carcinoma.
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Efficacy and safety of carboplatin with nab-paclitaxel versus docetaxel in older patients with squamous non-small-cell lung cancer (CAPITAL): a randomised, multicentre, open-label, phase 3 trial.