Learn About Stargardt Macular Degeneration

What is the definition of Stargardt Macular Degeneration?

Stargardt macular degeneration is a genetic eye disorder that causes progressive vision loss. This disorder affects the retina, the specialized light-sensitive tissue that lines the back of the eye. Specifically, Stargardt macular degeneration affects a small area near the center of the retina called the macula. The macula is responsible for sharp central vision, which is needed for detailed tasks such as reading, driving, and recognizing faces. In most people with Stargardt macular degeneration, a fatty yellow pigment (lipofuscin) builds up in cells underlying the macula. Over time, the abnormal accumulation of this substance can damage cells that are critical for clear central vision. In addition to central vision loss, people with Stargardt macular degeneration have problems with night vision that can make it difficult to navigate in low light. Some affected individuals also have impaired color vision. The signs and symptoms of Stargardt macular degeneration typically appear in late childhood to early adulthood and worsen over time.

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What are the causes of Stargardt Macular Degeneration?

In most cases, Stargardt macular degeneration is caused by mutations in the ABCA4 gene. Less often, mutations in the ELOVL4 gene cause this condition. The ABCA4 and ELOVL4 genes provide instructions for making proteins that are found in light-sensing (photoreceptor) cells in the retina.

How prevalent is Stargardt Macular Degeneration?

Stargardt macular degeneration is the most common form of juvenile macular degeneration, the signs and symptoms of which begin in childhood. The estimated prevalence of Stargardt macular degeneration is 1 in 8,000 to 10,000 individuals.

Is Stargardt Macular Degeneration an inherited disorder?

Stargardt macular degeneration can have different inheritance patterns.

Who are the top Stargardt Macular Degeneration Local Doctors?
Elite
Highly rated in
31
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Obstetrics and Gynecology
Ophthalmology

Sutter Health

Tracy Care Center

445 W Eaton Ave 
Tracy, CA 95376

Stephen Tsang is an Obstetrics and Gynecologist and an Ophthalmologist in Tracy, California. Dr. Tsang is rated as an Elite doctor by MediFind in the treatment of Stargardt Macular Degeneration. He is also highly rated in 31 other conditions, according to our data. His top areas of expertise are Stargardt Macular Degeneration, Late-Onset Retinal Degeneration, Retinitis Pigmentosa, and Retinopathy Pigmentary Mental Retardation. He is board certified in Obstetrics/gynecology and Ophthalmology and licensed to treat patients in California and New York. Dr. Tsang is currently accepting new patients.

Elite
Highly rated in
28
conditions
Ophthalmology

University of Iowa Health Care

University Of Iowa Hospitals & Clinics

200 Hawkins Dr 
Iowa City, IA 52242

Edwin Stone is an Ophthalmologist in Iowa City, Iowa. Dr. Stone has been practicing medicine for over 37 years and is rated as an Elite doctor by MediFind in the treatment of Stargardt Macular Degeneration. He is also highly rated in 28 other conditions, according to our data. His top areas of expertise are Late-Onset Retinal Degeneration, Stargardt Macular Degeneration, Retinitis Pigmentosa, and Age-Related Macular Degeneration. He is board certified in Ophthalmology and licensed to treat patients in Iowa. Dr. Stone is currently accepting new patients.

 
 
 
 
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Elite
Highly rated in
2
conditions

Medical University Of Graz

Graz, AT 

Rupert Strauss is in Graz, Austria. Strauss is rated as an Elite expert by MediFind in the treatment of Stargardt Macular Degeneration. He is also highly rated in 2 other conditions, according to our data. His top areas of expertise are Stargardt Macular Degeneration, Late-Onset Retinal Degeneration, Age-Related Macular Degeneration, and Cone Dystrophy.

What are the latest Stargardt Macular Degeneration Clinical Trials?
Bone Marrow Derived Stem Cell Ophthalmology Treatment Study II
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Phase 3, Multicenter, Randomized, Double-Masked, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Tinlarebant in the Treatment of Stargardt Disease in Adolescent Subjects
Who are the sources who wrote this article ?

Published Date:updated Last, November

Published By: National Institutes of Health

What are the Latest Advances for Stargardt Macular Degeneration?
Stargardt disease: A clinical case report of two sisters with different clinical development.
Systemic complement activation levels in Stargardt disease.
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Laser-induced choroidal neovascularization: A case report and some reflection on animal models for age-related macular degeneration.