Efficacy of Add-on Ketamine With Second-dose Midazolam for Prehospital Treatment of Epileptic Children With Status Epilepticus
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
The goal of this pragmatic, decentralized, pre-consented, event-driven, randomized controlled trial is to investigate the efficacy of add-on ketamine to second-dose midazolam for prehospital treatment of epileptic children with convulsive status epilepticus.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 16
Healthy Volunteers: f
View:
• Age from 2 to 16 years.
• Established diagnosis of epilepsy of at least 1 year duration.
• History of at least 1 episode of convulsive status epilepticus in the preceding 12 months.
Locations
Other Locations
Egypt
Department of Pediatrics at Sohag University Hospital
RECRUITING
Sohag
Contact Information
Primary
Elsayed Abdelkreem
d.elsayedmohammed@med.sohag.edu.eg
1114232126
Time Frame
Start Date: 2025-08-03
Estimated Completion Date: 2026-08-01
Participants
Target number of participants: 668
Treatments
Experimental: Ketamine + Midazolam
Active_comparator: Midazolam
Related Therapeutic Areas
Sponsors
Leads: Sohag University