A Comparative Study of Intravenous Versus Peribulbar Administration of Dexmedetomidine for Strabismus Surgery in Adults
Status: Completed
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Using various adjuvants has become a trend in regional anesthesia practice to improve the quality of anesthesia and prolong postoperative analgesia. Dexmedetomidine, an alpha-2 agonist has been proposed as a safe and effective adjunct capable of extending the duration of the single-shot block
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 60
Healthy Volunteers: f
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• The patient planned to perform a unilateral strabismus surgery
• Age: 20-60 years
• American Society of Anesthesiologists class I and II
Locations
Other Locations
Egypt
Aswan University Hospital
Aswān
Huda Fahmy
Aswān
Time Frame
Start Date: 2022-01-28
Completion Date: 2023-09-15
Participants
Target number of participants: 46
Treatments
Active_comparator: Peribulbar dexmedetomidine
The peribulbar block will be done using a mixture of 4 ml Lidocaine 2%, 4 ml Bupivacaine 0.5%, and 2 ml normal saline containing 50 μg dexmedetomidine perineurally (30 patients).
Active_comparator: Intravenous dexmedetomidine
The peribulbar block will be done using a mixture of 4 ml Lidocaine 2%, 4 ml Bupivacaine 0.5%, and 2 ml normal saline. Patients received 50 μg dexmedetomidine in 50 mL of normal saline administered as an infusion over 10 minutes, and given 10 minutes before the peribulbar block (30 patients).
Related Therapeutic Areas
Sponsors
Leads: Aswan University Hospital