The Effect of Administration of Sugammadex on the Occurrence of Emergence Agitation in Pediatric Strabismus Surgery-prospective Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The present trial conducted to demonstrate the administration of sugammadex as reversal of neuromuscular blockade agent reduces the incidence of emergence agitation (EA) comparing to neostigmine
Eligibility
Participation Requirements
Sex: All
Minimum Age: 4
Maximum Age: 7
Healthy Volunteers: t
View:
• Patients scheduled elective strabismus surgery aged 4-7 with American Society of Anesthesiologists (ASA) classification 1-3.
Locations
Other Locations
Republic of Korea
Konkuk University Medical Center
RECRUITING
Seoul
Contact Information
Primary
Yea-Ji Lee, M.D Ph. D
ladydaisy82@naver.com
+82-2-2030-5450
Time Frame
Start Date: 2023-12-01
Estimated Completion Date: 2025-08-15
Participants
Target number of participants: 76
Treatments
Active_comparator: group pyridostigmine
If TOF count is 1 or less, wait until it becomes 2 and then give the patient pyridostigmine dose of 350mcg/kg. If TOF count shows 4 with fade, 350mcg/kg of pyridostigmine is administered and without fade, 200mcg/kg is administered.
Active_comparator: group sugammadex
If TOF count shows 0 and PTC (posttetanic count) is 1 or more, sugammadex administered dose of 4mg/kg. If TOF count shows 1 or more, 2mg/kg is administered.
Related Therapeutic Areas
Sponsors
Leads: Konkuk University Medical Center