Synovitis
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Synovitis Overview

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Learn About Synovitis

What is the definition of Synovitis?
Synovitis is the inflammation of a synovial membrane, the layer of connective tissue that lines joints such as the shoulder, hip, knee, or ankle. Arthritis is one of the main causes of synovitis. Athletes and individuals with physically rigorous jobs are also particularly at risk of overusing joints and developing synovitis. 
What are the symptoms of Synovitis?
The main symptom of synovitis is joint pain, which can range in severity from person to person. Some individuals experience significant paint even if there is no swelling or inflammation of the joint. Individuals with synovitis may also experience bleeding at the affected joint(s).
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What are the current treatments for Synovitis?
The simplest treatment for synovitis involves rest to avoid further joint damage. Individuals with synovitis may also be prescribed disease-modifying antirheumatic drugs (DMARDs) or receive oral steroids to reduce inflammation. Physical therapy may aid with strengthening a joint and surrounding muscles, and in more serious cases, a physician may recommend a synovectomy, a procedure to remove the inflamed joint lining. 
Who are the top Synovitis Local Doctors?
Elite in Synovitis
Dr. Charles Peterfy
Radiology
Elite in Synovitis
Dr. Charles Peterfy
Radiology

Office

72 Rock Rd, 
Greenbrae, CA 
415-461-2086
Languages Spoken:
English

Charles Peterfy is a Radiologist practicing medicine in Greenbrae, California. Dr. Peterfy is rated as an Elite provider by MediFind in the treatment of Synovitis. He is also highly rated in 2 other conditions, according to our data. His clinical expertise encompasses Synovitis, Tenosynovitis, Horner Syndrome, Pigmented Villonodular Synovitis, and Tissue Biopsy.

Elite in Synovitis
Dr. Ali Guermazi
Radiology
Elite in Synovitis
Dr. Ali Guermazi
Radiology

Veterans Affairs Boston Healthcare System

1400 Vfw Pkwy, 
Boston, MA 
857-203-6448
Languages Spoken:
English

Ali Guermazi is a Radiologist practicing medicine in Boston, Massachusetts. Dr. Guermazi is rated as an Elite provider by MediFind in the treatment of Synovitis. He is also highly rated in 7 other conditions, according to our data. His clinical expertise encompasses Synovitis, Synovial Osteochondromatosis, Calcium Pyrophosphate Arthritis, Knee Replacement, and Endoscopy.

 
 
 
 
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Elite in Synovitis
Dr. Nicholas M. Bernthal
Pediatric Orthopedics
Elite in Synovitis
Dr. Nicholas M. Bernthal
Pediatric Orthopedics
403 West Adams Boulevard, 
Los Angeles, CA 
213-741-8325
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Nicholas Bernthal is a Pediatric Orthopedics provider practicing medicine in Los Angeles, California. Dr. Bernthal is rated as an Elite provider by MediFind in the treatment of Synovitis. He is also highly rated in 34 other conditions, according to our data. His clinical expertise encompasses Adult Soft Tissue Sarcoma, Bone Tumor, Synovitis, Osteotomy, and Hip Replacement. Dr. Bernthal is currently accepting new patients.

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What are the latest Synovitis Clinical Trials?
Phase 2, Single-arm Study to Investigate the Tolerability, Pharmacokinetics, Efficacy, and Safety of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor
Phase 2, Single-arm Study to Investigate the Tolerability, Pharmacokinetics, Efficacy, and Safety of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor
Enrollment Status: Recruiting
Publish Date: April 16, 2026
Intervention Type: Drug
Study Phase: Phase 2

Summary: The primary purpose of this study is to assess the tolerability, pharmacokinetics, and efficacy of pimicotinib in Japanese participants with TGCT

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A Multicenter, Randomized, Double-blind, Placebo-controlled, Proof of Concept Trial to Investigate the Efficacy and Safety of Intra-articular 4P004 in Subjects With Knee Synovitis and Osteoarthritis
A Multicenter, Randomized, Double-blind, Placebo-controlled, Proof of Concept Trial to Investigate the Efficacy and Safety of Intra-articular 4P004 in Subjects With Knee Synovitis and Osteoarthritis
Enrollment Status: Recruiting
Publish Date: April 14, 2026
Intervention Type: Drug
Study Phase: Phase 2

Summary: This phase 2a trial is an international, multicenter, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of one single intra-articular (IA) injection of 4P004 or placebo in: * patients between 40 and 80 years of age, * with synovitis and grade 2 to 4 osteoarthritis (OA) of the knee according to Kellgren and Lawrence (KL) classification.

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