Association of Systemic Immune Inflammatory Index with Disease Activity and Lupus Nephritis in Patients with Systemic Lupus Erythematosus
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
This study aims to investigate the association between the systemic immune-inflammation index and disease activity, as well as lupus nephritis in patients with systemic lupus erythematosus
Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: t
View:
• o Older than 16 years
‣ In a patient with SLE, patients who fulfill the criteria of the American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR).
⁃ In patients with LN, patients whose diagnosis is confirmed by kidney biopsy and pathohistological verification (WHO classification, and the International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification.
Locations
Other Locations
Egypt
Sohag Faculty
RECRUITING
Sohag
Contact Information
Primary
Shorouk Mohamed abdelmageed, master degree
Shrouk011107@med.sohag.edu.eg
02 +01099082079
Time Frame
Start Date: 2024-12-02
Estimated Completion Date: 2026-02
Participants
Target number of participants: 90
Treatments
patients diagnosed with systemic lupus and lupus nephritis
this group will include 30 patients, all patients will undergo the following: For the evaluation of SLE clinical disease activity SLEDAI ( systemic upus erythematosus disease activity index)scores will be recorded The SII (systemic immune inflammatory index) will be calculatedusing the following formula: SII = (neutrophil count × platelet count)/lymphocyte count.
patients diagnosed with systemic lupus without lupus nephritis
this group will also include 30 patients, all patients will undergo the following: For the evaluation of SLE clinical disease activity SLEDAI ( systemic upus erythematosus disease activity index)scores will be recorded The SII (systemic immune inflammatory index) will be calculated using the following formula: SII = (neutrophil count × platelet count)/lymphocyte count.
healthy control group
this group will also include 30 healthy controls , they will undergo the following: The SII (systemic immune inflammatory index) will be calculated using the following formula: SII = (neutrophil count × platelet count)/lymphocyte count.
Related Therapeutic Areas
Sponsors
Leads: Sohag University