Tay-Sachs Disease Latest Advances

Find the Latest Research About Tay-Sachs Disease

Last Updated: 04/28/2026

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Found 2198 publications

Pyrimethamine-based targeting of HEXA gene mutations in Tay-Sachs disease: a computational analysis.

Pyrimethamine-based targeting of HEXA gene mutations in Tay-Sachs disease: a computational analysis.

Journal: Journal of biomolecular structure & dynamics
Published: February 20, 2026

Correction: Vyas et al. Efficacy of Adeno-Associated Virus Serotype 9-Mediated Gene Therapy for AB-Variant GM2 Gangliosidosis. Int. J. Mol. Sci. 2023, 24, 14611.

Correction: Vyas et al. Efficacy of Adeno-Associated Virus Serotype 9-Mediated Gene Therapy for AB-Variant GM2 Gangliosidosis. Int. J. Mol. Sci. 2023, 24, 14611.

Journal: International journal of molecular sciences
Published: January 17, 2026

Bilateral Macular Cherry-Red Spots in Infantile Sandhoff Disease.

Bilateral Macular Cherry-Red Spots in Infantile Sandhoff Disease.

Journal: Ophthalmology. Retina
Published: January 15, 2026

Tay-Sachs disease models: From cellular and animal models to treatment perspectives.

Tay-Sachs disease models: From cellular and animal models to treatment perspectives.

Journal: Molecular genetics and metabolism
Published: January 15, 2026

B4Galnt1 Deficiency Reverses Severe Neurological Symptoms in a Mouse Model of Tay-Sachs Disease.

B4Galnt1 Deficiency Reverses Severe Neurological Symptoms in a Mouse Model of Tay-Sachs Disease.

Journal: Neuromolecular medicine
Published: January 04, 2026

Correction to 'A novel HEXA frameshift mutation identified in Angus cattle with GM2 gangliosidosis'.

Correction to 'A novel HEXA frameshift mutation identified in Angus cattle with GM2 gangliosidosis'.

Journal: Animal genetics
Published: January 04, 2026

Symptomatic Benefit of Acetyl-DL-Leucine for Cerebellar Ataxia in Juvenile Tay-Sachs Disease: A Pediatric Case and Literature Review.

Symptomatic Benefit of Acetyl-DL-Leucine for Cerebellar Ataxia in Juvenile Tay-Sachs Disease: A Pediatric Case and Literature Review.

Journal: Molecular syndromology
Published: November 25, 2025

Generation and characterization of induced pluripotent stem cell (iPSC) lines from patients affected with Tay-Sachs and Sandhoff disease.

Generation and characterization of induced pluripotent stem cell (iPSC) lines from patients affected with Tay-Sachs and Sandhoff disease.

Journal: Stem cell research
Published: November 19, 2025

Human Neuraminidase 3 reduces the severity of Tay-Sachs disease symptoms in a mouse model.

Human Neuraminidase 3 reduces the severity of Tay-Sachs disease symptoms in a mouse model.

Journal: Neurochemistry international
Published: November 17, 2025

A novel humanized mouse model exhibits neurobehavioral impairments and recapitulates key neuropathological features of infantile Tay-Sachs disease.

A novel humanized mouse model exhibits neurobehavioral impairments and recapitulates key neuropathological features of infantile Tay-Sachs disease.

Journal: Journal of neuroinflammation
Published: November 11, 2025

New mouse models of GM2 gangliosidoses.

New mouse models of GM2 gangliosidoses.

Journal: Lab animal
Published: October 31, 2025

3D bioprinted neural scaffolds: a transformative avenue for GM2 gangliosidosis therapy.

3D bioprinted neural scaffolds: a transformative avenue for GM2 gangliosidosis therapy.

Journal: Annals of medicine and surgery (2012)
Published: October 03, 2025
Showing 1-12 of 2,198

Last Updated: 04/28/2026