A Multicenter, Randomized, Self-controlled Exploratory Clinical Study of Hetrombopag Olamine Tablets for Thrombocytopenia Induced by Anti-tumor Treatment in Advanced Breast Cancer
This study now plans to explore the efficacy and safety of hetrombopag in cancer therapy-induced thrombocytopenia in advanced breast cancer, so as to further guide the clinical application of hetrombopag in chemotherapy-induced platelets.
• The patients signed the informed consent and voluntarily joined the study;
• Age 18-75 years old, male or female;
• Patients with advanced breast cancer diagnosed by histopathology or cytology, who are receiving and continue to receive the same chemotherapy regimen;
• Can accept the current chemotherapy regimen (must be platinum-containing chemotherapy regimen: lobaplatin, carboplatin, cisplatin, etc.) for at least 2 cycles;
• The first occurrence of platelets \<50×109/L in the current chemotherapy cycle;
• The investigator determines that the patient can receive hetrombopag administration;
• Neutrophil count ≥ 1.0×109/L, hemoglobin ≥ 80g/L before administration of Haitrombopag;
• Life expectancy at screening ≥ 12 weeks;
• ECOG: 0-1;
⁃ The main organ functions are normal, and there are no serious complications.