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Study on the Safety and Efficacy of Cryoablation Therapy for Thyroid Tumors

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical study is to learn if cryoablation works to treat thyroid tumors. It will also learn about the safety of cryoablation for thyroid tumors. The main questions it aims to answer are: * Does cryoablation shrink thyroid tumors over time? * What side effects or problems do participants have after cryoablation? Participants will receive cryoablation treatment guided by ultrasound. Researchers will track tumor size changes and check for any safety issues during follow-up visits.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

⁃ 【Group 1: Papillary Thyroid Carcinoma (PTC) patients】

• Pre-operative ultrasound evaluation shows the maximum tumor diameter \<1 cm;

• Papillary thyroid carcinoma (PTC) confirmed by ultrasound-guided fine-needle aspiration (FNA) biopsy;

• Solitary PTC confirmed by pre-operative ultrasound;

• Imaging examinations demonstrate no extrathyroidal invasion, cervical lymph node metastasis or distant metastasis.

⁃ 【Group 2: Benign thyroid nodule patients】

• Benign nodule confirmed by puncture biopsy;

• Preoperative ultrasound confirms solid nodule with maximum diameter greater than 2 cm;

• Patients refuse surgical treatment or cannot tolerate surgery, voluntarily receive thyroid ablation therapy and sign the informed consent form.

Locations
Other Locations
China
Chinese People's Liberation Army General Hospital
RECRUITING
Beijing
Contact Information
Primary
Yukun Luo, MD
lyk301@163.com
010-66939533
Time Frame
Start Date: 2026-02-09
Estimated Completion Date: 2030-01-10
Participants
Target number of participants: 108
Treatments
Active_comparator: Microwave Ablation Group
Patients receive conventional ultrasound-guided microwave ablation.
Experimental: Cryoablation Group
Participants undergo ultrasound-guided cryoablation, the investigational treatment evaluated in this study.
Related Therapeutic Areas
Sponsors
Leads: Yukun Luo

This content was sourced from clinicaltrials.gov