Learn About Total Intestinal Aganglionosis

Condition 101 content is not available at this time, but we are continually updating the site. Please check back.

However, there may be experts who have treated this or similar conditions in our Find a Doctor section and research may be available in our Latest Advances section.

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What are the Latest Advances for Total Intestinal Aganglionosis?
Characterizing the use of botulinum toxin in patients with Hirschsprung disease treated at referral institutions for pediatric colorectal surgery.
Hirschsprung disease managed with one-stage transanal endorectal pullthrough in a low-resource setting without frozen section.
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Laparoscopic-assisted Soave procedure for Hirschsprung disease: 10-year experience with 106 cases.
What are the latest Total Intestinal Aganglionosis Clinical Trials?
The Enteric Nervous System as Modulator of Mucosal Immune Cells

Summary: Hirschsprung's disease (HD) is diagnosed shortly after birth and is characterized by the presence of megacolon. HD is caused when ganglion cells of the enteric nervous system (ENS) in the wall of the large intestine do not develop before birth. This results in a lack of gastrointestinal motility and leads to stool obstruction. It is known that ablation of enteric nerves is associated with intestin...

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Prospective Randomised Blinded Study Comparing Full Thickness Biopsy and Rectal Suction Biopsies in the Diagnosis of Mb: Hirschsprung

Summary: The objective of this prospective study is to compare the diagnostic accuracy of rectal suction biopsy (RSB) compared to full thickness rectal biopsy (FTB) in the diagnosis of Hirschsprungs Disease (HD) in children. The secondary objective to compare cost-effectiveness of the two procedures