Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter
Who is this study for? Patients with Hyperthyroidism
What treatments are being studied? Iodine-Potassium Iodide 5%-10% Oral and Topical Solution
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The purpose of this study is to assess if preoperative treatment with Lugol's solution prior to thyroidectomy can reduce the surgical complications hypoparathyroidism and laryngeal nerve palsy
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Hyperthyroidism accepted for thyroidectomy due to toxic nodular goiter with free T4 \<30 pmol/L or Graves' disease
• Signed informed consent
Locations
Other Locations
Sweden
Department of Endocrinology, Karolinska University Hospital
RECRUITING
Solna
Contact Information
Primary
Jan Calissendorff, MD, PhD
jan.calissendorff@regionstockholm.se
+46(0)8 51770000
Backup
Fredric Hedberg, MD
fredric.hedberg@regionstockholm.se
+46(0)8 51770000
Time Frame
Start Date: 2021-11-18
Estimated Completion Date: 2025-08
Participants
Target number of participants: 182
Treatments
Experimental: Iodine Potassium Iodide solution
Participants receive Iodine Potassium Iodide solution oral drops 3 times per day for 10 Days prior to thyroidectomy in addition to standard preoperative treatment
No_intervention: No intervention
Participants continue with standard preoperative treatment
Related Therapeutic Areas
Sponsors
Leads: Jan Calissendorff