Latest Advances

  • Condition: Acute Kidney Injury (AKI) Caused by Septic Shock
  • Journal: Zhonghua wei zhong bing ji jiu yi xue
  • Treatment Used: Fluid Resuscitation Strategy Guided by Pulse-Indicated Continuous Cardiac Output (PiCCO) Monitoring vs Early Goal-Directed Therapy (EGDT)
  • Number of Patients: 94
  • Published —
This study compared the effectiveness of fluid resuscitation (used to restore circulating volume, preserve vital organs and tissue perfusion) strategy guided by pulse-indicated continuous cardiac output (monitors patient’s haemodynamic, or blood flow, status; PiCCO) monitoring versus early goal-directed therapy (approach to diagnosis and treatment of sepsis at time of presentation; EGDT) on renal (kidney) function in patients with acute kidney injury (abrupt loss of kidney function; AKI) caused by septic shock (significant drop in blood pressure that can lead to respiratory or heart failure, stroke, failure of other organs, and death).
  • Condition: Septic Shock
  • Journal: The American journal of emergency medicine
  • Treatment Used: Intravenous Thiamine
  • Number of Patients: 0
  • Published —
The aim of this meta-analysis was to explore the impact of intravenous thiamine on treatment effectiveness of septic shock.
  • Condition: Toxic Shock Syndrome Following COVID-19 Infection
  • Journal: American journal of ophthalmology case reports
  • Treatment Used: Corticosteroid Eye Drops
  • Number of Patients: 1
  • Published —
This article examined the case of a patient with toxic shock syndrome (serious but uncommon bacterial infection) following COVID-19 (a pandemic infection caused by a coronavirus) infection treated with corticosteroid eye drops (used to prevent permanent damage to the eye).
  • Condition: Sepsis-induced Cardiogenic Shock
  • Journal: Lancet (London, England)
  • Treatment Used: Venoarterial Extracorporeal Membrane Oxygenation
  • Number of Patients: 212
  • Published —
In this study, researchers evaluated the outcomes of venoarterial extracorporeal membrane oxygenation (VA-ECMO) for the treatment of sepsis-induced cardiogenic shock.
  • Condition: COVID-19
  • Journal: BioEssays : news and reviews in molecular, cellular and developmental biology
  • Treatment Used: Beta-adrenergic Blockers
  • Number of Patients: 0
  • Published —
This article discusses the potential use of beta-adrenergic blockers as a treatment for COVID-19.
  • Condition: Sepsis and Septic Shock, COVID-19
  • Journal: Stem cells translational medicine
  • Treatment Used: Mesenchymal Stromal Cells
  • Number of Patients: 0
  • Published —
This article discusses mesenchymal stromal cells as a potential alternative treatment for acute respiratory distress syndrome (ARDS) associated with COVID-19.
  • Condition: Septic Shock
  • Journal: JAMA
  • Treatment Used: Ascorbic Acid, Corticosteroids, and Thiamine
  • Number of Patients: 205
  • Published —
This study evaluated the effect of ascorbic acid (used to prevent or treat low levels of vitamin C), corticosteroids (drugs that can effectively reduce inflammation), and thiamine (vitamin B1) on organ injury in patients with septic shock (when sepsis, the body’s extreme response to an infection, leads to life-threatening low blood pressure).
  • Condition: Septic Shock
  • Journal: Critical care (London, England)
  • Treatment Used: Norepinephrine
  • Number of Patients: 929
  • Published —
This review of the literature evaluated the impact of early and late start of norepinephrine support on outcomes in patients with septic shock.
  • Condition: Severe Sepsis and Shock
  • Journal: Advances in therapy
  • Treatment Used: Methylene Blue
  • Number of Patients: 1
  • Published —
This article describes using methylene blue to treat patients with severe sepsis and shock.
  • Condition: Septic Shock in Children
  • Journal: The Israel Medical Association journal : IMAJ
  • Treatment Used: Methylene Blue
  • Number of Patients: 0
  • Published —
The study researched the use of methylene blue for children who are in septic shock.
  • Condition: Septic Shock
  • Journal: Medicine
  • Treatment Used: Continuous Renal Replacement Therapy and the Endotoxin Removal Device oXiris
  • Number of Patients: 1
  • Published —
In this study, researchers evaluated the outcomes of treating septic shock using continuous renal replacement therapy combined with the new endotoxin removal device called oXiris.
  • Condition: Children with Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS)
  • Journal: The Lancet. Child & adolescent health
  • Treatment Used: Invasive Ventilation, Vasoactive Infusions, Steroids, Intravenous Immunoglobulin, and Biologic Therapies
  • Number of Patients: 0
  • Published —
This study analyzed the intensive care admissions of children with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS).
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