COMPARATIVE EFFECTS OF ZINC AND PROBIOTICS ON NEONATAL INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
Study will evaluate effects of oral zinc and probiotics supplementation in neonates who have indirect hyperbilirubinemia and are receiving phototherapy. Aim is to compare efficacy of these two drugs in clearing bilirubin and reducing duration of phototherapy. Neonates will be randomly assigned to receive either drug alongside phototherapy.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 28 days
Healthy Volunteers: f
View:
• 1\. Term or Near term neonates 2. Age \<7 days at enrollment 3. Bilirubin levels within phototherapy range according to NICE bilirubin threshold charts 4. No identifiable pathology 5. Tolerating oral feeds 6. Parental or Guardian written informed consent taken.
Locations
Other Locations
Pakistan
Sadiq Abbasi Hospital, QAMC, Bahawalpur
RECRUITING
Bahawalpur
Contact Information
Primary
Malik M. Umair Fazal, MBBS, FCPS Paediatrics
umair.malik1622@gmail.com
+923318682681
Backup
Dr. Muhammad Anwar, MBBS, FCPS Neonatology
hmanwar157@yahoo.com
+923216820943
Time Frame
Start Date: 2025-08-07
Estimated Completion Date: 2026-05-07
Participants
Target number of participants: 110
Treatments
Experimental: Zinc group
Participants in this group will receive oral zinc following neonatal dosing guidelines.
Experimental: Probiotics group
Participants in this group will receive oral probiotics following neonatal dosing guidelines.
Related Therapeutic Areas
Sponsors
Leads: Quaid-e-Azam Medical College