Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management.
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The objective of this study is to ascertain the diagnostic threshold of end-tidal carbon monoxide (ETCOc, adjusted for ambient CO levels) within the first three days postpartum, stratified by neonatal age at birth. Additionally, the study aims to evaluate the concordance of the risk range of ETCOc, as measured by non-dispersive infrared spectroscopy, with existing literature, and to assess the reliability of this technology in the management of neonatal hyperbilirubinemia.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 28 days
Healthy Volunteers: t
View:
• Newborns with gestational age of ≥ 37 weeks and birth weight of ≥ 2.5 kg;
• Newborns delivered by either vaginal delivery or cesarean section and with hospital stay of ≥ 3 days.
Locations
Other Locations
China
4th Affiliated Hospital, School of Medicine, Zhejiang University
RECRUITING
Yiwu
Contact Information
Primary
Yixiang Wu
laibujilene@163.com
+8613600643385
Time Frame
Start Date: 2025-12-05
Estimated Completion Date: 2027-07-01
Participants
Target number of participants: 100
Treatments
Experimental: term neonates
The non-dispersive infrared spectroscopy technique was employed to measure the end-tidal carbon monoxide (ETCOc) levels in newborns at intervals of 12, 24, 48, and 72 hours post-birth.
Related Therapeutic Areas
Sponsors
Leads: The Fourth Affiliated Hospital of Zhejiang University School of Medicine