Y-SCOPE Study: a Pilot Study to Assess Optimal Prevention and Outcome Improvement in Young Ischemic Stroke
Objective: Assess the feasibility of the study by evaluating participant eligibility, consent rates, adherence to interventions, and retention rates. * Secondary
Objectives: Compare health outcomes between the intervention and control groups, including: Improvement in cardiovascular health scores. Reduction in major cardiovascular events. Enhancements in physical activity, diet, sleep quality, and smoking cessation. Changes in inflammatory markers in the blood. Potential Benefits While this is a pilot study and may not provide definitive evidence of effectiveness, it aims to develop a tailored secondary prevention strategy for young stroke patients. The personalized approach could lead to better management of risk factors, improved quality of life, and a reduction in recurrent strokes and other cardiovascular events. Participation Participants will be required to attend scheduled clinic visits, engage in counseling sessions, and use the provided wearable device consistently. Regular monitoring and feedback will be integral parts of the program. Confidentiality All personal health information and data collected during the study will be kept confidential and used solely for research purposes. This study is conducted by the Neurology Department and Stroke Unit at the IRCCS Mondino Foundation.
• Age: 18 to 65 years.
• Diagnosis: Acute ischemic stroke or high-risk transient ischemic attack (TIA) (ABCD2 score ≥ 6).
• Cardiovascular Health Status: Low or moderate cardiovascular health, assessed by the American Heart Association's Life's Essential 8 (LE8) Score.
• Functional Independence: Modified Rankin Scale (mRS) score of 0 to 2 at enrollment.
• Ability to Participate: Participants must be able to adhere to the study's follow-up visits and intervention requirements.