Transient Neonatal Diabetes Mellitus Overview

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Learn About Transient Neonatal Diabetes Mellitus

What is the definition of Transient Neonatal Diabetes Mellitus?
Transient neonatal diabetes mellitus (TNDB) is a type of diabetes that appears within the first few weeks of life but is transient; affected infants go into remission within a few months, with possible relapse to permanent diabetes in adolescence or adulthood. Affected individuals have slow growth before birth followed by hyperglycemia, dehydration and failure to thrive in infancy. Approximately 70% of cases are caused by the overactivity of certain genes in a region of the long (q) arm of chromosome 6 called 6q24. These cases are referred to as 6q24-related TNDB; most (but not all) of these cases are not inherited. Other genetic causes include genetic changes in the KCNJ11 and ABCC8 genes, which usually cause permanent neonatal diabetes.
What are the alternative names for Transient Neonatal Diabetes Mellitus?
  • Transient neonatal diabetes mellitus
  • Chromosome 6-associated transient diabetes mellitus
  • DMTN
  • Diabetes mellitus, 6q24-related transient neonatal
  • Diabetes mellitus, transient neonatal
  • TNDM
  • TNDM1
Who are the top Transient Neonatal Diabetes Mellitus Local Doctors?
Elite in Transient Neonatal Diabetes Mellitus
Deborah G. Mackay
Elite in Transient Neonatal Diabetes Mellitus
Deborah G. Mackay
Southampton, ENG, GB 

Deborah Mackay practices in Southampton, United Kingdom. Ms. Mackay is rated as an Elite expert by MediFind in the treatment of Transient Neonatal Diabetes Mellitus. Her top areas of expertise are Transient Neonatal Diabetes Mellitus, Beckwith-Wiedemann Syndrome, Macroglossia, and Russell-Silver Dwarfism.

Elite in Transient Neonatal Diabetes Mellitus
Sarah E. Flanagan
Elite in Transient Neonatal Diabetes Mellitus
Sarah E. Flanagan
Exeter, ENG, GB 

Sarah Flanagan practices in Exeter, United Kingdom. Ms. Flanagan is rated as an Elite expert by MediFind in the treatment of Transient Neonatal Diabetes Mellitus. Her top areas of expertise are Congenital Hyperinsulinism, Low Blood Sugar, Transient Neonatal Diabetes Mellitus, Newborn Low Blood Sugar, and Pancreatectomy.

 
 
 
 
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Elite in Transient Neonatal Diabetes Mellitus
Helene Cave
Elite in Transient Neonatal Diabetes Mellitus
Helene Cave
Paris, FR 

Helene Cave practices in Paris, France. Ms. Cave is rated as an Elite expert by MediFind in the treatment of Transient Neonatal Diabetes Mellitus. Her top areas of expertise are RASopathies, Noonan Syndrome, Juvenile Myelomonocytic Leukemia (JMML), and Transient Neonatal Diabetes Mellitus.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center