Transposition of the Great Arteries: Prenatal Anatomical and Hemodynamic Findings Associated With Perinatal Outcomes
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This prospective study will examine whether transient maternal hyperoxygenation is useful as a diagnostic test to more accurately detect TGA patients with poor vs. good neonatal intra-cardiac mixing of blood, based on the in-utero response to oxygen exposure. This study is Health Canada regulated
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• Fetus with simple TGA +/- small VSD
• Intention of active postnatal management after birth
Locations
Other Locations
Canada
The Hospital For Sick Children
RECRUITING
Toronto
Contact Information
Primary
Edgar Jaeggi, MD
edgar.jaeggi@sickkids.ca
+1(416)813-7500
Backup
Mike Seed, MBBS
mike.seed@sickkids.ca
+1(416)813-7500
Time Frame
Start Date: 2018-09-20
Estimated Completion Date: 2025-01-31
Participants
Target number of participants: 40
Treatments
Experimental: Oxygen gas
10-15 L/min of oxygen by face mask for up to 45 minutes for the MRI and up to 30 minutes for the echocardiogram.
Authors
Mika Saito, Mike Seed
Related Therapeutic Areas
Sponsors
Leads: The Hospital for Sick Children