Tricuspid Regurgitation Clinical Trials

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Prospective Study of Lead-associated Tricuspid Regurgitation in Patients Undergoing New Transvalvular Lead Insertion

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this clinical trial is to record the incidence of newly developed or worsening tricuspid valve regurgitation (TR) following the implantation of a pacemaker or defibrillator with a transvenous lead. To collect this data, a transthoracic echocardiogram (TTE) with 3D imaging of the tricuspid valve (TV) will be performed before and after pacemaker implantation, with particular emphasis on assessing the tricuspid valve. Additionally, routine follow-up visits will be conducted at 6 and 12 months post-intervention, during which a TTE, ECG, NT-proBNP measurement, and pacemaker check will be performed.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• medically indicated for pacemaker, ICD- or CRT implantation

• No previous diagnosis of severe tricuspid regurgitation on enrollment

• No existing transvalvular device (must be first implantation)

• No other diagnosed severe valvular heart disease

• Not previous diagnosis with pre-capillary pulmonary hypertension

• No previous diagnosis of structural disease of the right ventricle (i.e. ACM, cardiac sarcoidosis, carcinoid...)

Locations
Other Locations
Germany
Herz- und Diabeteszentrum NRW
RECRUITING
Bad Oeynhausen
Contact Information
Primary
Hazem Omran, MD
homran@hdz-nrw.de
+49 5731 970
Backup
Lena Riemke-Maw, BSc
lriemke-maw@hdz-nrw.de
+49 5731 97
Time Frame
Start Date: 2024-07-19
Estimated Completion Date: 2027-01-30
Participants
Target number of participants: 200
Treatments
Pacemaker-standard
Only pacemaker with standard positioning (no ICD leads, no LBBaP)
ICD
any ICD leads through tricuspid valve
LBBaP
Left bundle branch area pacing leads
Related Therapeutic Areas
Sponsors
Leads: Hazem Omran

This content was sourced from clinicaltrials.gov