Flexible Band Versus Rigid Ring Annuloplasty for the Correction of Tricuspid

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Tricuspid regurgitation is common in patients with heart valve disease, both flexible band and rigid ring annuloplasty can correct this anomaly. However, there is no data to address which one can bring more benefits to these patients with combined heart valve disease. This study aims to prospectively compare the efficacy and long term outcomes of flexible band versus rigid ring annuloplasty for the correction of tricuspid regurgitation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• 1\. Subject must be 18 years and 80 years at time of consent and must not be a member of a vulnerable population.

• 2\. Subject or a legally authorized representative (where allowed per local regulations) must provide written informed consent prior to any trial related procedure.

• 3\. Subjects with moderate or greater tricuspid regurgitation determined by the assessment of a qualifying transthoracic echocardiogram (TTE) and/or transesophageal echocardiogram (TEE).

• 4\. Subjects with moderate tricuspid regurgitation will only be included in the trial if moderate tricuspid regurgitation is accompanied by a tricuspid annular diameter of ≥ 40mm as measured by echocardiography.

• 5\. Isolated functional symptomatic tricuspid regurgitation of moderate to severe or greater, with annular dilatation of ≥ 40mm;

• 6\. Requirement for concomitant left heart valve surgery;

• 7\. Requirement for concomitant coronary artery surgery;

• 8\. Requirement for concomitant atrial fibrillation surgery;

• 9\. Available and able to return to the study site for post-procedural follow-up examination;

Locations
Other Locations
China
The First Affiliated Hospital of Nanjing Medical University
RECRUITING
Nanjing
Contact Information
Primary
Yong-feng Shao, MD
yongfengshao30@hotmail.com
025-83714511
Time Frame
Start Date: 2021-01-01
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 300
Treatments
Active_comparator: Group Ring
Patients in Group Ring will undergo tricuspid rigid ring annuloplasty
Active_comparator: Group Band
Patients in Group Band will undergo flexible band annuloplasty
Related Therapeutic Areas
Sponsors
Collaborators: Affiliated Hospital of Nantong University
Leads: The First Affiliated Hospital with Nanjing Medical University

This content was sourced from clinicaltrials.gov