Annuloplasty Rings and Band Post-Market Clinical Follow-Up (ARB-PMCF) Study

Status: Recruiting
Location: See all (17) locations...
Intervention Type: Device
Study Type: Observational
SUMMARY

ARB-PMCF is a multicenter, observational study of the safety and performance of Abbott annuloplasty devices used in surgical repair of mitral and tricuspid valve regurgitation. The devices included in this study are the SJM™ Rigid Saddle Ring and SJM Séguin Annuloplasty Ring, indicated for mitral valve repair, and the SJM Tailor™ Annuloplasty Ring and SJM Tailor Annuloplasty Band, indicated for mitral or tricuspid repair. Participants will be enrolled prior to undergoing mitral or tricuspid valve repair surgery including an Abbott annuloplasty implant and will complete annual follow-up visits through five years from implant. The study is being conducted to meet post-market clinical follow-up requirements of the European Union Medical Device Directives.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Subject is expected to undergo cardiac surgery in ≤90 days including at least one of the following:

‣ implant of a Rigid Saddle Ring, Séguin Ring or a full Tailor Ring without cut zone removal for MR repair

⁃ implant of a full Tailor Ring without cut zone removal for TR repair, or

⁃ implant of a Tailor Band or partial Tailor Ring with cut zone removed for primary TR repair.

• Subject's cardiac surgery will be performed by a study investigator.

• Subject will be ≥18 years old at the time of their annuloplasty implant(s).

• Subject provides written informed consent and agrees to comply with all required study visits and procedures.

Locations
United States
North Carolina
Duke University Hospital
WITHDRAWN
Durham
Wisconsin
University of Wisconsin Hospital and Clinics
WITHDRAWN
Madison
Other Locations
Estonia
Tartu University Hospital
RECRUITING
Tartu
France
CHU de Besançon - Jean Minjoz
RECRUITING
Besançon
Hopital Cardiovasculaire et Pneumologique Louis Pradel
RECRUITING
Lyon
Germany
Herzzentrum-Bremen Klinikum Links der Weser
RECRUITING
Bremen
Herzzentrum Dresden, Universitätsklinik an der Technischen Universität Dresden
RECRUITING
Dresden
Universitätsklinikum Jena
RECRUITING
Jena
Herzchirurgische Abteilung Klinikum Passau
RECRUITING
Passau
Universitätsklinikum Würzburg
COMPLETED
Würzburg
Italy
Policlinico S.Orsola-Malpighi
RECRUITING
Bologna
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
RECRUITING
Milan
Ospedale Luigi Sacco
WITHDRAWN
Milan
Ospedale San Raffaele - Cardiac
RECRUITING
Milan
Ospedale Umberto I
RECRUITING
Turin
Netherlands
Catharina Ziekenhuis
RECRUITING
Eindhoven
Spain
Hospital Alvaro Cunqueiro
RECRUITING
Vigo
Contact Information
Primary
Karine Miquel
karine.miquel@abbott.com
+32 479 60 01 07
Backup
Leslie Ornelas
leslie.ornelas@abbott.com
+14803067436
Time Frame
Start Date: 2021-02-01
Estimated Completion Date: 2031-03
Participants
Target number of participants: 550
Treatments
Group 1: Primary mitral disease repair surgery with an Abbott annuloplasty ring implant
Group 1 will enroll 200 subjects undergoing surgical repair of primary mitral regurgitation that includes annuloplasty with an Abbott SJM Rigid Saddle Ring, Séguin Ring or full Tailor Ring without cut zone removal. Enrollment must include at least 50 subjects implanted with each ring model. In primary mitral regurgitation, backflow through the closed valve is caused by disease intrinsic to the mitral valve tissue itself.
Group 2: Secondary mitral disease repair surgery with an Abbott annuloplasty ring implant
Group 2 will enroll 200 subjects undergoing surgical repair of secondary mitral regurgitation that includes annuloplasty with an Abbott SJM Rigid Saddle Ring, Séguin Ring or full Tailor Ring without cut zone removal. Enrollment must include at least 50 subjects implanted with each ring model. In secondary mitral regurgitation, backflow through the closed valve is secondary to diseases of the surrounding myocardium, rather than caused by disease of the valve tissue itself.
Group 3: Primary tricuspid disease repair surgery with a full Tailor Ring implant
Group 3 will enroll up to 50 subjects undergoing surgical repair of primary tricuspid regurgitation that includes annuloplasty with a full Abbott SJM Tailor Ring without cut zone removal. In primary tricuspid regurgitation, backflow through the closed valve is caused by disease intrinsic to the tricuspid valve tissue itself.
Group 4: Secondary tricuspid disease repair surgery with a full Tailor Ring implant
Group 4 will enroll up to 50 subjects undergoing surgical repair of secondary tricuspid regurgitation that includes annuloplasty with a full Abbott SJM Tailor Ring without cut zone removal. In secondary tricuspid regurgitation, backflow through the closed valve is secondary to diseases of the surrounding myocardium, rather than caused by disease of the valve tissue itself.
Group 5: Primary tricuspid disease repair surgery with a partial Tailor Ring or Tailor Band implant
Group 4 will enroll up to 50 subjects undergoing surgical repair of secondary tricuspid regurgitation that includes posterior annuloplasty with either a partial Abbott SJM Tailor Ring with cut zone removed or an Abbott SJM Tailor Band. In primary tricuspid regurgitation, backflow through the closed valve is caused by disease intrinsic to the tricuspid valve tissue itself.
Sponsors
Leads: Abbott Medical Devices

This content was sourced from clinicaltrials.gov