Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation study is open to a subset of patients with disorders of sex development (DSD) which is associated with the risk of malignancy and a high risk of infertility or sterility. For these patients, experimental gonadal tissue cryopreservation is the only fertility preservation option available. The overall objective of this study is to determine the safety and efficacy of gonadal tissue cryopreservation as a method of preserving fertility and/or restoring hormonal function in patients with gonadal dysgenesis who are at risk of decreased fertility potential or malignancy.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 30
Healthy Volunteers: f
View:

• \< 30 years of age

• Individuals diagnosed with a disorder of sex development who have any risk for malignancy in their gonadal tissue and will have their gonads removed for a clinical indication

• Individuals diagnosed with a disorder of sex development who are at risk of primary ovarian insufficiency (POI) due to an underlying genetic condition

Locations
United States
Colorado
University of Colorado
RECRUITING
Aurora
Contact Information
Primary
Kristine Corkum, MD
Kristine.Corkum@childrenscolorado.org
(720) 777-6174
Backup
Jocelyn Phipers
Jocelyn.Phipers@cuanschutz.edu
303-724-7807
Time Frame
Start Date: 2021-08-16
Estimated Completion Date: 2031-06-30
Participants
Target number of participants: 50
Treatments
Experimental: Cryopreservation of gonadal tissue
Enrolled participants will undergo gonadal tissue processing, freezing and cryopreservation after the standard care (gonadectomy, gonadal tissue histologic examination)
Sponsors
Leads: University of Colorado, Denver

This content was sourced from clinicaltrials.gov