US-based Clinical Sub-study of DASH-Obesity: Explainable AI for Family-Centric Transdiagnostic Personalized Weight Control Across Multiple Conditions
This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a family-centered digital health intervention designed to support adolescents and young adults with overweight/obesity and chronic conditions, including type 1 diabetes (T1D) and asthma. The intervention combines personalized educational content, wearable-device monitoring, psychometric assessments, and explainable artificial intelligence (AI) to improve mental well-being, quality of life, and adherence to healthy lifestyle behaviors. A total of 280 families will participate in a 3-month intervention with remote monitoring and follow-up assessments.
• Adult caregiver (aged 18 years or older) of an adolescent or young adult aged 12 to 21 years diagnosed with Type 1 Diabetes (T1D) or asthma.
• The caregiver is actively involved in the management of the adolescent's or young adult's condition.
• The adolescent or young adult must meet one of the following criteria:
• T1D and normal weight (BMI between the 10th and 85th percentile), or
• T1D and overweight/obesity (BMI ≥85th percentile), or
• Asthma and overweight/obesity (BMI ≥85th percentile).
• Willingness to participate in the Adhera Caring Digital Program-Obesity (ACDP-O).
• Access to a smartphone or internet-enabled device compatible with the study application.
• Willingness to provide self-reported information regarding the adolescent's or young adult's health status, including disease-related and anthropometric measures.
• For caregivers of participants with T1D, willingness to share continuous glucose monitoring (CGM) information.