Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics (DREAM-ON) - An Observational Cohort Study From the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC)

Status: Recruiting
Location: See all (13) locations...
Intervention Type: Device
Study Type: Observational
SUMMARY

The DREAM-ON study will investigate whether continuous glucose monitoring (CGM) is useful to predict risk for developing diabetes mellitus (DM) and pre-diabetes mellitus (PDM), the need for insulin therapy among those who develop DM, and to determine whether CGM can provide insight into the pathophysiology and DM subtype among participants who have experienced an episode of acute pancreatitis (AP). Thus, the results of the DREAM-ON study could inform future clinical practice guidelines for the management AP as well as potentially extending the licensing authorization for CGM to include use in patients with pancreatogenic (Type 3c) DM.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Diagnosis of acute pancreatitis (AP) 0-90 days prior to enrollment

• Participant fully understands and is able to participate in all aspects of the study, including providing informed consent, completion of case report forms, telephone interviews, metabolic testing, and planned longitudinal follow-ups

Locations
United States
California
Cedars-Sinai Medical Center
RECRUITING
Los Angeles
University of Southern California
RECRUITING
Los Angeles
Stanford University
RECRUITING
Stanford
Florida
University of Florida
RECRUITING
Gainesville
AdventHealth
RECRUITING
Orlando, Fl
Illinois
Northwestern University
RECRUITING
Chicago
University of Illinois at Chicago
RECRUITING
Chicago
Indiana
Indiana University
RECRUITING
Indianapolis
Maryland
Johns Hopkins University
RECRUITING
Baltimore
Minnesota
University of Minnesota
RECRUITING
Minneapolis
Ohio
Ohio State University
RECRUITING
Columbus
Pennsylvania
University of Pittsburgh
RECRUITING
Pittsburgh
Washington
Benaroya Research Institute
RECRUITING
Seattle
Contact Information
Primary
Melissa A Butt, DrPH
mbutt1@pennstatehealth.psu.edu
717-531-1258
Backup
Ron Zimmerman, MPA
rzimmerman1@pennstatehealth.psu.edu
717-531-3851
Time Frame
Start Date: 2024-10-16
Estimated Completion Date: 2027-03-31
Participants
Target number of participants: 800
Treatments
CGM
Continuous Glucose Monitoring (CGM)
Sponsors
Collaborators: Indiana University, University of Southern California, University of Florida, Stanford University, Benaroya Research Institute, University of Pittsburgh, University of Minnesota, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), AdventHealth, Northwestern University, Cedars-Sinai Medical Center, Johns Hopkins University, Ohio State University, University of Illinois at Chicago
Leads: Milton S. Hershey Medical Center

This content was sourced from clinicaltrials.gov