What is the definition of Type B Insulin Resistance Syndrome?

Insulin resistance type B syndrome is a very rare form of diabetes that occur in individuals with an autoimmune disorder, usually lupus erythematosus. In insulin resistance type B syndrome, abnormal antibodies block insulin, causing a build-up of glucose (sugar) in the blood. Insulin resistance type B syndrome mainly affects middle-aged females.

What are the symptoms for Type B Insulin Resistance Syndrome?

Symptoms of insulin resistance type B syndrome may include sudden onset of diabetes that is difficult to control; weight loss; increased appetite; darkening of the skin on the face, underarms, and around the groin (acanthosis nigricans); high testosterone levels in women; irregular or absent menstruation; abnormal hair growth on the face and back in women (hirsutism); and low blood sugar.

What are the current treatments for Type B Insulin Resistance Syndrome?

Treatment for insulin resistance type B syndrome involves very high doses of insulin and metformin to control high blood sugar and immunosuppressive drugs, such as rituximab, to treat the underlying autoimmune disorder.
  • Condition: Newly Diagnosed Type 2 Diabetes Mellitus
  • Journal: Endocrine
  • Treatment Used: Nigella Sativa Oil versus Metformin
  • Number of Patients: 0
  • Published —
The purpose of the study was to investigate the potential benefits of Nigella Sativa oil as sole therapy in newly diagnosed type 2 diabetes mellitus patients.
  • Condition: severe type B insulin resistance
  • Journal: Diabetes care
  • Treatment Used: combined immunosuppressive therapy
  • Number of Patients: 22
  • Published —
The purpose of the study was to analyze the effectiveness of combined immunosuppressive therapy in the management of severe type B insulin resistance, a form of diabetes.
Clinical Trial
  • Status: Recruiting
  • Phase: N/A
  • Intervention Type: Procedure
  • Participants: 52
  • Start Date: February 5, 2021
Liver and Metabolic Effects of Insulin Pump Therapy in a Population of Type 2 Diabetics With Non-alcoholic Hepatic Steatosis
Clinical Trial
  • Status: Not yet recruiting
  • Intervention Type: Diagnostic Test
  • Participants: 60
  • Start Date: January 2019
The Effect Of Direct Acting Antiviral Drugs on miRNA-122 And Insulin Resistance In Chronic HCV Patients