Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut inflammation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6
Maximum Age: 21
Healthy Volunteers: f
View:

• Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC)

Locations
United States
Washington
Seattle Children's Hospital
RECRUITING
Seattle
Contact Information
Primary
Mason E Nuding, BS
mason.nuding@seattlechildrens.org
206-987-0055
Time Frame
Start Date: 2024-05-10
Estimated Completion Date: 2030-01
Participants
Target number of participants: 200
Treatments
Inflammatory Bowel Disease
Participants will enroll before their initial diagnostic procedure. After pathology results are reported, participants will be categorized based on the assigned diagnoses: Inflammatory Bowel Disease (IBD) \[Crohn's disease (CD), ulcerative colitis (UC), and Indeterminate Colitis (IC)\] vs Disorders of the Brain-Gut Interactions (DGBI).~Participation in the IBD cohort will last for three years.
Disorders of the Brain-Gut Interactions
Participants will enroll before their initial diagnostic procedure. After pathology results are reported, participants will be categorized based on the assigned diagnoses: Inflammatory Bowel Disease (IBD) \[Crohn's disease (CD), ulcerative colitis (UC), and Indeterminate Colitis (IC)\] vs Disorders of the Brain-Gut Interactions (DGBI).~-The DGBI cohort will be subdivided into: Esophageal Disorder, Gastroduodenal Disorder, Bowel Disorder, Centrally Mediated Disorders of GI Pain, Gallbladder and Sphincter of Oddi Disorder, Anorectal Disorder, Childhood Functional GI Disorders: Neonate/Toddler, Childhood Functional GI Disorders: Child/Adolescent~Participation in the DGBI cohort will include the initial sample and data collection as well an one further medical record extraction at month 24.
Sponsors
Leads: Seattle Children's Hospital
Collaborators: Allen Institute

This content was sourced from clinicaltrials.gov