A Novel Simplified Endoscopic Score aiMed at Evaluating Ulcerative cOlitis Activity Through TXI, RDI and NBI Vascular Assessment and at prEdicting Clinical Outcome and Its Applicability in an arTificial Intelligence System: the MONET Study

Status: Recruiting
Location: See all (11) locations...
Intervention Type: Procedure, Other, Diagnostic test
Study Type: Observational
SUMMARY

This international multicentre prospective study aims to develop a new simple score using enhanced endoscopic techniques which focus on the vascular features of the colon and reliably distinguish between a quiescent and a mild inflammation in ulcerative colitis (UC). The diagnostic performance of the new score in defining disease activity/remission compared to existing endoscopic and histological scores and predict long-term clinical outcomes will be evaluated. The study also aims to adapt current artificial intelligence (AI) algorithms for enhanced endoscopic techniques to improve standardization in UC disease assessment and outcome prediction.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Adult patients aged 18 to 75 years old

• Established diagnosis of UC (for at least six months in duration), independently from their active treatment

• Undergoing endoscopy for disease activity assessment or cancer surveillance.

Locations
Other Locations
Belgium
University of Leuven
NOT_YET_RECRUITING
Leuven
Germany
Klinikum Luneburg
NOT_YET_RECRUITING
Lüneburg
Ireland
University College Cork
RECRUITING
Cork
Italy
University of Bari
NOT_YET_RECRUITING
Bari
Ospedale S. Maria del Prato
NOT_YET_RECRUITING
Feltre
Istituto Clinico Humanitas
NOT_YET_RECRUITING
Milan
University Vita-Salute San Raffaele
NOT_YET_RECRUITING
Milan
University of Naples
RECRUITING
Naples
University of Pavia
NOT_YET_RECRUITING
Pavia
Japan
Showa University
NOT_YET_RECRUITING
Tokyo
Singapore
Changi General Hospital
NOT_YET_RECRUITING
Singapore
Contact Information
Primary
Michelle O'Riordan
moriordan@ucc.ie
+353 (0)21 4901759
Time Frame
Start Date: 2024-11-04
Estimated Completion Date: 2027-09-30
Participants
Target number of participants: 300
Treatments
Ulcerative Colitis patients
UC patients who have been scheduled for colonoscopy for disease assessment or surveillance
Sponsors
Leads: University College Cork
Collaborators: Olympus

This content was sourced from clinicaltrials.gov

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