Analysis of Microplastics in Pediatric Inflammatory Bowel Disease Using Raman Spectroscopy: A Multi-Matrix Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

The goal of this observational study is to measure and compare the presence of microplastics in children with inflammatory bowel disease (IBD) and children without IBD. The main questions it aims to answer are: Are microplastics detectable in different biological samples from children? Are there differences in microplastic burden between children with and without IBD? Researchers will collect biological samples including: intestinal tissue (from routine endoscopy), stool, urine, blood. Raman spectroscopy will be used to detect and characterize microplastics in each sample type. Participants will not receive any medication or intervention as part of this study. All samples will be collected during standard clinical procedures.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 18
Healthy Volunteers: f
View:

• Age \<18 years

• Undergoing clinically indicated gastrointestinal endoscopy

• For IBD group: confirmed diagnosis of Crohn's disease or ulcerative colitis

• For control group: no current or past diagnosis of IBD

Locations
Other Locations
Poland
Medical University of Gdańsk, Department of Pediatrics, Gastroenterology, Allergolgy and Nutrition
RECRUITING
Gdansk
Contact Information
Primary
Dominika Marszk, MD
dsierdzinska@gumed.edu.pl
+48609619101
Time Frame
Start Date: 2025-06-15
Estimated Completion Date: 2026-06
Participants
Target number of participants: 40
Treatments
Pediatric IBD group
Children diagnosed with inflammatory bowel disease (Crohn's disease or ulcerative colitis) undergoing clinically indicated endoscopy. Biological samples, including intestinal biopsies, stool, urine, and blood, will be collected and analyzed for microplastic content using Raman spectroscopy.
Control group
Children without a diagnosis of IBD undergoing endoscopy for non-inflammatory indications (e.g., polyps, anemia). Biological samples, including intestinal biopsies, stool, urine, and blood, will be collected and analyzed for microplastic content using Raman spectroscopy.
Sponsors
Leads: Medical University of Gdansk

This content was sourced from clinicaltrials.gov