The PRECISION-T2D Study: Precision Nutrition Study for Type 2 Diabetes

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Food plays a crucial role in determining blood glucose levels, especially in people with type 2 diabetes. Precision nutrition, which involves individually tailored dietary interventions, can be a powerful tool in managing blood glucose levels in people with type 2 diabetes. Previous studies found that changes in gut microbiota resulted from the dietary intervention, such as plant-based diet, might subsequently lead to different glycemic responses, and then different health outcomes. In this study, the investigators will characterize the blood glucose dynamics and gut microbiota of individuals with type 2 diabetes. They aim to assess the influence of plant-based diet on gut microbiota; they will also investigate the influence of gut microbiota on glycemic responses. Additionally, a series of individual N-of-1 trails will be integrated to compare the effects of a white bread breakfast and a whole wheat bread breakfast on glucose metabolism at the individual level.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 35
Maximum Age: 75
Healthy Volunteers: f
View:

• Diagnosed with type 2 diabetes;

• Living in Hangzhou for at least five years;

• Have the willingness or ability to complete the intervention and sample collection

Locations
Other Locations
China
Hangzhou Third People's Hospital
RECRUITING
Hangzhou
Westlake University
RECRUITING
Hangzhou
Contact Information
Primary
Ju-Sheng Zheng, PhD
zhengjusheng@westlake.edu.cn
86-0571-88112056
Time Frame
Start Date: 2023-07-17
Estimated Completion Date: 2033-12-01
Participants
Target number of participants: 200
Treatments
Experimental: Plant-based diet
Participants in this arm will be recommended to consume more fiber-rich foods, including whole grains, fruits, legumes and vegetables; to moderate their intake of fish, eggs and dairy products; and to avoid other animal products. All participants are instructed not to modify their exercise habits during the intervention period.
Experimental: Conventional diabetic diet
Participants in this arm will be recommended to have a diet following 2023 Chinese Diabetes Society guidelines. All participants are instructed not to modify their exercise habits during the intervention period.
Related Therapeutic Areas
Sponsors
Leads: Westlake University
Collaborators: The Third People's Hospital of Hangzhou

This content was sourced from clinicaltrials.gov