Effect of a Vegetarian Meal on the Pathophysiology of Insulin Response: a Randomized Controlled Crossover Study in Patients With Type 2 Diabetes and Obesity
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The role of diet in determining glucose intolerance and its progression towards T2DM has been extensively investigated. A 2017 meta-analysis showed that a vegetarian diet is inversely associated with the risk of developing diabetes. Vegetarians, with the same baseline risk, are half as likely to develop T2DM than those following an omnivorous diet. Therefore, vegetarian nutrition could have important clinical implications in the dietary management of diabetic patients.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:
• Age 18-70 years
• Diagnosis of T2DM
• In treatment with diet alone or single oral drug metformin
• BMI ≥ 30
• HbA1c between 6.0 and 9.0% (42-75 mmol/mol)
• Signature of the informed consent
Locations
Other Locations
Italy
IRCCS Ospedale San Raffaele
RECRUITING
Milan
Contact Information
Primary
Emanuele Bosi, MD
bosi.emanuele@hsr.it
0226432818
Backup
Andrea Pontara
pontara.andrea@hsr.it
+393473064605
Time Frame
Start Date: 2022-06-09
Estimated Completion Date: 2024-09-30
Participants
Target number of participants: 20
Treatments
Experimental: Meal 2
Meal with a vegetarian protein
Active_comparator: Meal 1
Meal with animal protein
Related Therapeutic Areas
Sponsors
Leads: IRCCS San Raffaele