Differential Effects of HIIT vs. TRE on Type 2 Diabetes Risk in Youth and Younger Adults

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and young adults.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 14
Maximum Age: 30
Healthy Volunteers: t
View:

• Adolescents (age 14-17 years old with sex- and race-specific BMI percentile ≥85th) and young adults with overweight and obesity (age 18 to 30 years old with BMI ≥25 kg/m2)

Locations
United States
New York
Syracuse University
RECRUITING
Syracuse
Contact Information
Primary
Wonhee Cho, MS, PhD Candidate
wcho02@syr.edu
+16267270270
Backup
Joon Young Kim, PhD, PhD
jkim291@syr.edu
Time Frame
Start Date: 2024-03-15
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 40
Treatments
Experimental: High-intensity interval training
HIIT: The 4-week HIIT intervention will use a stationary bicycle performed 3 times/week (a total of 12 sessions over the 4-week), performing at the CRL. All participants will perform a 20-minute HIIT protocol (20 repetitions of 10-seconds work time followed by 50-seconds resting/active recovery for the first two weeks, and 10 repetitions of 20-seconds work time followed by 100-seonds resting/active recovery for the rest of two weeks; targeted 90% HRmax) after 5-minute warm-up (10% HRmax). The supervisor (PI: Joon Young Kim and/or Graduate researcher: Wonhee Cho) will provide encouragement and supervision for exercise adherence. Heart rate (Polar, Polar Electro Oy, Kempele, Finland) and rating of perceived exertion (RPE; detail described in the questionnaire section) will be recorded.
Experimental: Time-restricted eating
Participants randomized into the TRE group will be instructed to consume all their calories within a 10-hour period. We will instruct participants that they can choose their time-window (early TRE \[7am - 5pm\] or late TRE \[1pm - 11pm\]), but it must remain constant for the duration of the study. Further, we will give no restrictions on the type of foods and/or the quantities individuals can consume. We will ask individuals to maintain their diet for the duration of the study. Participants will be given clear instructions on their diet and how to use the MyFitnessPal application. Participants will have their total daily energy requirement calculated using the following formula (Basal metabolic rate \[BMR\] x activity level) and will be told to eat that amount within their allotted time window. BMR will be calculated when participants have their body composition taken by the InBody. Participants will be told to start their 4-week diet the following day after visit.
No_intervention: Control Group
Participants randomized into the control group will be told to maintain their daily lifestyle and dietary habits for the duration of the four weeks.
Related Therapeutic Areas
Sponsors
Leads: Syracuse University
Collaborators: State University of New York - Upstate Medical University

This content was sourced from clinicaltrials.gov