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Magnetic Compression Anastomosis in Side-to-Side Duodeno-ileostomy Versus Semaglutide in Adults With Obesity and Type 2 Diabetes (MAGvMED Study)

Status: Recruiting
Location: See location...
Intervention Type: Device, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Compare use of the Magnet System in side-to-side duodeno-ileostomy (Surgery) with semaglutide (Medication).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Body Mass Index (BMI) between 30 - 40 kg/m2 and qualifies for obesity treatment at the discretion of the treating investigator (i.e., must be assessed to qualify for both surgery and medication treatment to justify randomization).

• Type 2 diabetes (T2D defined as HbA1c ≥ 6.5%).

• Participant agrees to refrain from additional metabolic and bariatric (MBS) or reconstructive surgery that would affect body weight for the duration of the study.

• Participant agrees to refrain from taking any additional semaglutide-containing or other GLP-1RA medication for the duration of the study, regardless of randomization assignment (i.e., Surgery or Medication).

⁃ Participant has been informed of the nature of the study and is willing and able to comply with requirements, including randomization, and provides written informed consent to participate in the study.

Locations
Other Locations
Canada
Westmount Surgical Center
RECRUITING
Westmount
Contact Information
Primary
Lisa Griffin Vincent, PhD, MA
clinical@gtmetabolic.com
+1 763-200-1416
Backup
Josh Schumacher
clinical@gtmetabolic.com
+1 763-200-1416
Time Frame
Start Date: 2026-03
Estimated Completion Date: 2028-06
Participants
Target number of participants: 20
Treatments
Active_comparator: Surgery Arm
Magnet System
Active_comparator: Medication Arm
Semaglutide
Related Therapeutic Areas
Sponsors
Leads: GT Metabolic Solutions, Inc.

This content was sourced from clinicaltrials.gov

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