Type 2 Diabetes (T2D) Clinical Trials

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Integrated Assessment of Pancreatic Dysfunction in Patients With Type 2 Diabetes: a Cross-sectional Study Protocol

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to better understand how the pancreas works in adults with type 2 diabetes. The study focuses on both hormone production (endocrine function) and digestive function (exocrine function) of the pancreas. The main questions it aims to answer are: * Can problems with the pancreas help identify a different type of diabetes called pancreatogenic diabetes? * How are blood markers and pancreas structure related to pancreatic function? Participants will: * Have blood tests to measure glucose, insulin, and other markers * Provide a stool sample to assess digestive function * Undergo an ultrasound examination of the pancreas * Answer questions about digestive symptoms The study will take place during a single visit in outpatient clinics.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 74
Healthy Volunteers: f
View:

• • adult patients of Kazakh nationality aged 18 to 74 years

• diagnosis of T2DM established according to ADA criteria and documented in medical records

• disease duration ≤5 years

• absence of ketoacidosis episodes within the last 6 months

Locations
Other Locations
Kazakhstan
Outpatient clinics of Aktobe region, West Kazakhstan Marat Ospanov Medical University
RECRUITING
Aktobe
Contact Information
Primary
Mengtay S Makashova
ersultanbeknur@gmail.com
+77058440060
Time Frame
Start Date: 2025-07-07
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 310
Treatments
Group/Cohort Label T2DM without EPI by fecal elastase-1
Adults with type 2 diabetes mellitus classified as not having exocrine pancreatic insufficiency according to fecal elastase-1 levels.
Group/Cohort Label T2DM without EPI by PEI-Q
Adults with type 2 diabetes mellitus classified as not having exocrine pancreatic insufficiency according to Pancreatic Exocrine Insufficiency Questionnaire (PEI-Q) results.
Sponsors
Leads: West Kazakhstan Marat Ospanov Medical University
Collaborators: Universitatea de Stat de Medicina si Farmacie Nicolae Testemiţanu

This content was sourced from clinicaltrials.gov